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偶然分枝杆菌偶然生物变种以及龟分枝杆菌两个亚群对亚胺培南、头孢美唑、头孢西丁和阿莫西林-克拉维酸的敏感性。

Susceptibilities of Mycobacterium fortuitum biovar. fortuitum and the two subgroups of Mycobacterium chelonae to imipenem, cefmetazole, cefoxitin, and amoxicillin-clavulanic acid.

作者信息

Wallace R J, Brown B A, Onyi G O

机构信息

Department of Microbiology, University of Texas Health Center, Tyler 75710.

出版信息

Antimicrob Agents Chemother. 1991 Apr;35(4):773-5. doi: 10.1128/AAC.35.4.773.

Abstract

MICs of imipenem, cefoxitin, cefmetazole, and amoxicillin-clavulanic acid were determined against 100 strains of Mycobacterium fortuitum and 200 strains of Mycobacterium chelonae. Imipenem and cefmetazole were more active against M. fortuitum than cefoxitin was, and imipenem (which inhibited 39% of strains at 8 micrograms/ml) was the only beta-lactam active against M. chelonae subsp. chelonae.

摘要

测定了亚胺培南、头孢西丁、头孢美唑和阿莫西林-克拉维酸对100株偶然分枝杆菌和200株龟分枝杆菌的最低抑菌浓度(MIC)。亚胺培南和头孢美唑对偶然分枝杆菌的活性比头孢西丁更强,并且亚胺培南(在8微克/毫升时可抑制39%的菌株)是唯一对龟分枝杆菌龟亚种有活性的β-内酰胺类药物。

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