Department of Electronic, Computer Science and Automatic Engineering, La Rábida Polytechnic School, University of Huelva, 21819 Palos de Frontera, Spain.
IEEE Trans Med Imaging. 2011 Jan;30(1):146-58. doi: 10.1109/TMI.2010.2064333. Epub 2010 Aug 9.
This paper presents a new supervised method for blood vessel detection in digital retinal images. This method uses a neural network (NN) scheme for pixel classification and computes a 7-D vector composed of gray-level and moment invariants-based features for pixel representation. The method was evaluated on the publicly available DRIVE and STARE databases, widely used for this purpose, since they contain retinal images where the vascular structure has been precisely marked by experts. Method performance on both sets of test images is better than other existing solutions in literature. The method proves especially accurate for vessel detection in STARE images. Its application to this database (even when the NN was trained on the DRIVE database) outperforms all analyzed segmentation approaches. Its effectiveness and robustness with different image conditions, together with its simplicity and fast implementation, make this blood vessel segmentation proposal suitable for retinal image computer analyses such as automated screening for early diabetic retinopathy detection.
本文提出了一种新的数字视网膜图像血管检测的有监督方法。该方法使用神经网络 (NN) 方案进行像素分类,并计算由基于灰度和矩不变量的特征组成的 7 维向量表示像素。该方法在广泛用于此目的的公共 DRIVE 和 STARE 数据库上进行了评估,因为它们包含血管结构已被专家精确标记的视网膜图像。该方法在两组测试图像上的性能均优于文献中其他现有方法。该方法在 STARE 图像的血管检测方面尤其准确。将其应用于该数据库(即使 NN 是在 DRIVE 数据库上训练的)也优于所有分析的分割方法。其在不同图像条件下的有效性和鲁棒性,以及其简单性和快速实现,使得这种血管分割方法适用于视网膜图像的计算机分析,例如自动筛查早期糖尿病视网膜病变。