Xinjiang Medical University, the Department of Endocrinology, First Affiliate Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China.
J Clin Hypertens (Greenwich). 2010 Sep;12(9):741-5. doi: 10.1111/j.1751-7176.2010.00349.x. Epub 2010 Jul 16.
This study was designed to evaluate the prevalence of the metabolic syndrome (MetS), impaired fasting blood glucose (IFG), insulin resistance (IR), hypertriglyceridemia (HTG), and low high-density lipoprotein cholesterol (HDL-C) in adult Uygur and Kazak populations. Questionnaires, blood pressure, anthropometric measurement, and fasting glucose were evaluated. The age-adjusted prevalence of MetS and IFG was 3.43- and 1.47-fold higher, respectively, in Uygurs compared with Kazaks. The prevalence of IR and HTG was 1.33- and 2.22-fold higher, respectively, in Uygurs compared with Kazaks. In addition, the prevalence of low HDL-C was 4.05-fold higher in Uygurs compared with Kazaks. These data depicted greater risk for cardiometabolic syndrome in Uygurs compared with Kazaks. In addition, all prevalence with the exception of low HDL-C was greater in men compared with women in both ethnic groups. For body mass index (BMI)<24, 24 to 28, and ≥28 kg/m2, the prevalence of MetS, HTG, and low HDL-C was higher in Uygurs than Kazaks at the same BMI level. For individuals with a BMI between 24 and 28, the prevalence of IR but not IFG was significantly greater in Uygurs than Kazaks. At BMI≥28, neither IFG nor IR was overtly different between the two ethnic groups.
本研究旨在评估代谢综合征（MetS）、空腹血糖受损（IFG）、胰岛素抵抗（IR）、高三酰甘油血症（HTG）和低高密度脂蛋白胆固醇（HDL-C）在维吾尔族和哈萨克族成年人中的流行情况。评估了问卷调查、血压、人体测量和空腹血糖。维吾尔族人群的 MetS 和 IFG 的年龄校正患病率分别比哈萨克族高 3.43 倍和 1.47 倍。维吾尔族人群的 IR 和 HTG 的患病率分别比哈萨克族高 1.33 倍和 2.22 倍。此外，维吾尔族人群的低 HDL-C 患病率比哈萨克族高 4.05 倍。这些数据表明维吾尔族人群患心血管代谢综合征的风险高于哈萨克族人群。此外，在两个民族中，除了低 HDL-C 之外，所有患病率在男性中均高于女性。对于 BMI<24、24 至 28 和≥28 kg/m2，维吾尔族人群的 MetS、HTG 和低 HDL-C 的患病率在相同 BMI 水平下均高于哈萨克族人群。对于 BMI 在 24 至 28 之间的个体，IR 的患病率但不是 IFG 的患病率在维吾尔族人群中明显高于哈萨克族人群。在 BMI≥28 时，IFG 和 IR 在两个民族之间均无明显差异。
