Moore G E, Morgan R T, Quinn L A, Woods L K
In Vitro. 1978 Mar;14(3):301-6. doi: 10.1007/BF02616040.
A transitional cell carcinoma cell line, COLO 232, was derived from a primary urinary bladder tumor in a Caucasian male. In culture, COLO 232 retained distinct uroepithelial phenotypic traits and produced both carcinoembryonic antigen and adrenocorticotropic hormone. COLO 232 had a chromosome mode of 58 and retained the X and Y chromosomes. Ten marker chromosomes were identified. COLO 232 will be of value for biochemical and immunological studies.
一种移行细胞癌细胞系COLO 232，源自一名白种男性的原发性膀胱肿瘤。在培养过程中，COLO 232保留了明显的尿路上皮表型特征，并产生癌胚抗原和促肾上腺皮质激素。COLO 232的染色体众数为58，并保留了X和Y染色体。鉴定出10条标记染色体。COLO 232在生化和免疫学研究中将具有价值。
