Khatam Anbia Eye Hospital, Eye Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Am J Ophthalmol. 2010 Dec;150(6):780-9. doi: 10.1016/j.ajo.2010.06.013. Epub 2010 Oct 8.
To evaluate and compare central corneal thickness measurements using rotating Scheimpflug camera, scanning-slit topography, and ultrasound pachymetry in virgin, healthy corneas.
Prospective, observational, cross-sectional study.
Central corneal thickness in 157 healthy eyes of 157 patients without ocular abnormalities other than refractive errors was measured, in a sequential order, once with rotating Scheimpflug camera and scanning-slit topography and 3 times with ultrasound pachymetry as the last part of examination. All measurements were performed by a single experienced examiner. The results from scanning-slit topography are given with and without correction for "acoustic correction factor" of 0.92.
The average measurements of central corneal thickness by rotating Scheimpflug imaging, scanning-slit pachymetry, and ultrasound were 537.15 ± 32.98 μm, 542.06 ± 39.04 μm, and 544.07 ± 34.75 μm, respectively. The mean differences between modalities were 6.92 μm between rotating Scheimpflug and ultrasound (P < .0001), 2.01 μm between corrected scanning-slit and ultrasound (P = .204), and 4.91 μm between corrected scanning-slit and rotating Scheimpflug imaging (P = .001). According to Bland-Altman analysis, highest agreement was between ultrasonic and rotating Scheimpflug pachymetry.
In the assessment of normal corneas, rotating Scheimpflug topography measures central corneal thickness values with higher agreement to ultrasound pachymetry.
评估和比较旋转式 Scheimpflug 相机、扫描式眼前节分析系统和超声角膜测厚仪在正常、健康角膜中的中央角膜厚度测量值。
前瞻性、观察性、横断面研究。
对 157 例屈光不正患者的 157 只健康眼，按顺序依次使用旋转式 Scheimpflug 相机和扫描式眼前节分析系统进行一次中央角膜厚度测量，然后使用超声角膜测厚仪进行 3 次测量。所有测量均由一位经验丰富的检查者完成。扫描式眼前节分析系统的结果在不考虑 0.92 的“声速校正因子”和考虑该校正因子的情况下分别给出。
旋转式 Scheimpflug 成像、扫描式眼前节分析系统和超声测量的中央角膜厚度平均值分别为 537.15 ± 32.98 μm、542.06 ± 39.04 μm 和 544.07 ± 34.75 μm。各模态之间的平均差异分别为旋转式 Scheimpflug 成像与超声之间相差 6.92 μm（P <.0001），校正后的扫描式眼前节分析系统与超声之间相差 2.01 μm（P =.204），校正后的扫描式眼前节分析系统与旋转式 Scheimpflug 成像之间相差 4.91 μm（P =.001）。根据 Bland-Altman 分析，超声与旋转式 Scheimpflug 角膜测厚仪之间的一致性最高。
在评估正常角膜时，旋转式 Scheimpflug 眼前节分析系统测量的中央角膜厚度值与超声角膜测厚仪具有更高的一致性。
