Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia 30602, United States.
Org Lett. 2010 Nov 5;12(21):4936-9. doi: 10.1021/ol1022036.
A microwave-assisted, one-pot, three-step Sonogashira cross-coupling-desilylation-cycloaddition sequence was developed for the convenient preparation of 1,4-disubstituted 1,2,3-triazoles starting from a range of halides, acyl chlorides, ethynyltrimethylsilane, and azides.
发展了一种微波辅助、一锅三步 Sonogashira 交叉偶联-脱硅烷基化-环加成序列,用于从各种卤化物、酰氯、乙炔基三甲基硅烷和叠氮化物出发,方便地制备 1,4-取代的 1,2,3-三唑。