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本文引用的文献

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The effect of the pH of the medium during growth on the enzymic activities of bacteria (Escherichia coli and Micrococcus lysodeikticus) and the biological significance of the changes produced.生长过程中培养基的pH值对细菌（大肠杆菌和溶壁微球菌）酶活性的影响以及所产生变化的生物学意义。
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pH homeostasis in Escherichia coli: measurement by 31P nuclear magnetic resonance of methylphosphonate and phosphate.大肠杆菌中的pH稳态：通过甲基膦酸酯和磷酸盐的31P核磁共振进行测量
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6271-5. doi: 10.1073/pnas.78.10.6271.
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Cytoplasmic pH mediates pH taxis and weak-acid repellent taxis of bacteria.细胞质pH介导细菌的pH趋化性和弱酸驱避性趋化性。
J Bacteriol. 1981 Mar;145(3):1209-21. doi: 10.1128/jb.145.3.1209-1221.1981.
4
Change in intracellular pH of Escherichia coli mediates the chemotactic response to certain attractants and repellents.大肠杆菌细胞内pH值的变化介导了对某些引诱剂和驱避剂的趋化反应。
J Bacteriol. 1981 Mar;145(3):1196-208. doi: 10.1128/jb.145.3.1196-1208.1981.
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Synthesis of biodegradative threonine dehydratase in Escherichia coli: role of amino acids, electron acceptors, and certain intermediary metabolites.大肠杆菌中生物降解性苏氨酸脱水酶的合成：氨基酸、电子受体和某些中间代谢物的作用
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Plasmid insertion mutagenesis and lac gene fusion with mini-mu bacteriophage transposons.利用微小噬菌体转座子进行质粒插入诱变和乳糖操纵子基因融合
J Bacteriol. 1984 May;158(2):488-95. doi: 10.1128/jb.158.2.488-495.1984.
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Escherichia coli intracellular pH, membrane potential, and cell growth.大肠杆菌细胞内pH值、膜电位与细胞生长
J Bacteriol. 1984 Apr;158(1):246-52. doi: 10.1128/jb.158.1.246-252.1984.
8
Determination of the transcription direction of the exuT gene in Escherichia coli K-12: divergent transcription of the exuT-uxaCA operons.大肠杆菌K-12中exuT基因转录方向的确定：exuT-uxaCA操纵子的双向转录
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Bacterial regulation: global regulatory networks.细菌调控：全局调控网络
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10
Regulation of cytoplasmic pH in bacteria.细菌中细胞质pH的调节
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大肠杆菌中新型基因座alx的碱性诱导

Alkaline induction of a novel gene locus, alx, in Escherichia coli.

作者信息

Bingham R J, Hall K S, Slonczewski J L

机构信息

Department of Biology, Kenyon College, Gambier, Ohio 43022.

出版信息

J Bacteriol. 1990 Apr;172(4):2184-6. doi: 10.1128/jb.172.4.2184-2186.1990.

DOI:10.1128/jb.172.4.2184-2186.1990
PMID:2108134
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC208722/
Abstract

A novel pH-regulated locus inducible over 100-fold in alkaline media was identified in Escherichia coli through screening of 93,000 Mu dI1734 (lacZ Kmr) operon fusions at pH 6.5 and pH 8.5. Four lacZ fusions that showed expression only at the higher pH were mapped at 67.5 min by P1 transduction crosses. The locus was designated alx.

摘要

通过在pH 6.5和pH 8.5条件下筛选93,000个Mu dI1734（lacZ Kmr）操纵子融合体，在大肠杆菌中鉴定出一个在碱性培养基中诱导表达可超过100倍的新型pH调节位点。通过P1转导杂交将四个仅在较高pH下显示表达的lacZ融合体定位在67.5分钟处。该位点被命名为alx。