Baudouin S V, Waterhouse J C, Tahtamouni T, Smith J A, Baxter J, Howard P
Department of Medicine, Royal Hallamshire Hospital, Sheffield.
Thorax. 1990 Mar;45(3):195-8. doi: 10.1136/thx.45.3.195.
The use of long term domiciliary oxygen therapy in the Sheffield area from June to August 1987 has been surveyed. Of the 74 patients prescribed long term domiciliary oxygen therapy, 64 were visited at home. These had arterial blood gas tensions or oxygen saturation measured (while breathing oxygen and air), and the indications for long term domiciliary oxygen therapy were examined retrospectively. Fifty two patients had chronic bronchitis and emphysema, the remainder having pneumoconiosis, bronchiectasis, fibrosing alveolitis, and congestive cardiac failure. Of the 54 cases where indications for treatment could be compared with the Department of Health and Social Security (DHSS) guidelines, only 23 (43%) met the full DHSS criteria before the start of treatment. The median length of treatment was 16 months. At follow up 51 patients had an arterial oxygen tension (PaO2) greater than 8.0 kPa when breathing oxygen. They had a significantly higher PaO2 when breathing air than before long term oxygen therapy (6.7 (SD 1.2) kPa before oxygen treatment, 7.6 (1.4) kPa on reassessment). A similar change was seen in the 23 patients assessed as recommended by the DHSS (6.1 (0.8) kPa; 7.2 (1.2]. PaO2 during the breathing of air was less than 7.3 kPa at reassessment in only 21 (33%) patients. Thirteen patients had carboxyhaemoglobin concentrations above 2.5%, the 95th centile of the distribution in nonsmokers in the laboratory.
对1987年6月至8月期间谢菲尔德地区长期家庭氧疗的使用情况进行了调查。在74例接受长期家庭氧疗的患者中,64例接受了家访。对这些患者进行了动脉血气张力或血氧饱和度测量(在吸氧和呼吸空气时),并对长期家庭氧疗的指征进行了回顾性检查。52例患者患有慢性支气管炎和肺气肿,其余患者患有尘肺、支气管扩张、肺纤维化和充血性心力衰竭。在54例可将治疗指征与卫生和社会保障部(DHSS)指南进行比较的病例中,只有23例(43%)在治疗开始前符合DHSS的全部标准。治疗的中位时长为16个月。随访时,51例患者在吸氧时动脉血氧张力(PaO2)大于8.0 kPa。他们呼吸空气时的PaO2明显高于长期氧疗前(氧疗前为6.7(标准差1.2)kPa,重新评估时为7.6(1.4)kPa)。在按照DHSS建议评估的23例患者中也观察到了类似变化(6.1(0.8)kPa;7.2(1.2)kPa)。重新评估时,只有21例(33%)患者呼吸空气时的PaO2低于7.3 kPa。13例患者的碳氧血红蛋白浓度高于2.5%,这是实验室中非吸烟者分布的第95百分位数。