Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Vaccine. 2011 Feb 1;29(6):1332-8. doi: 10.1016/j.vaccine.2010.10.061. Epub 2010 Dec 21.
This study aimed to ascertain the coverage of vaccination against pandemic influenza in individuals aged over 6 months for whom vaccination is indicated due to a chronic health condition using as data source clinical information recorded in the primary care clinical history. Of all those for whom vaccination was indicated (1,114,632), 14.6% (162,616) finally received the vaccine. There were statistically significance differences in coverage for sex (16.5% for men and 13.1% for women), age groups (5% for people under 30 years and 20% for those over 60), number of chronic conditions (11.1% for one condition, 22.5% for two conditions, and 31.3% for three or more conditions) and depending on the chronic health condition considered. The probability of being vaccinated increased with male sex, age, number of indications, type of medical card (lower among no income) and having been vaccinated against 2009 season influenza. We concluded that the coverage finally reached for those people with an indication due to chronic health condition in the H1N1 campaign was much lower than expected and wished. It is essential to investigate the different factors that could have intervened in the behavior of the population so that more efficient approaches can be adopted in future influenza pandemics.
本研究旨在确定因慢性健康状况而被指示接种流感大流行疫苗的 6 个月以上个体的疫苗接种覆盖率,使用初级保健临床病史中记录的临床信息作为数据源。在所有被指示接种疫苗的人群中(1,114,632 人),最终有 14.6%(162,616 人)接种了疫苗。在性别(男性为 16.5%,女性为 13.1%)、年龄组(30 岁以下人群为 5%,60 岁以上人群为 20%)、慢性疾病数量(一种疾病为 11.1%,两种疾病为 22.5%,三种或更多疾病为 31.3%)以及所考虑的慢性健康状况方面,覆盖率存在统计学差异。接种疫苗的概率随着男性、年龄、指示数量、医疗卡类型(低收入人群接种率较低)和 2009 年季节性流感疫苗接种而增加。我们得出结论,在 H1N1 大流行期间,因慢性健康状况而被指示接种疫苗的人群最终接种率远低于预期和期望。必须调查可能影响人群行为的不同因素,以便在未来的流感大流行中采取更有效的方法。