Alcohol and Drug Analytics Unit, National Institute for Health and Welfare, Helsinki, Finland.
Forensic Sci Int. 2011 May 20;208(1-3):173-9. doi: 10.1016/j.forsciint.2010.11.026. Epub 2010 Dec 22.
The performance of eight on-site oral fluid drug screening devices was studied in Belgium, Finland and the Netherlands as a part of the EU-project DRUID. The main objective of the study was to evaluate the reliability of the devices for testing drivers suspected of driving under the influence of drugs (DUID). The performance of the devices was assessed by their ability to detect substances using cut-offs which were set at sufficiently low levels to allow optimal detection of positive DUID cases. The devices were evaluated for the detection of amphetamine(s), cannabis, cocaine, opiates and benzodiazepines when the relevant test was incorporated. Methamphetamine, MDMA and PCP tests that were included in some devices were not evaluated since there were too few positive samples. The device results were compared with confirmation analysis results in oral fluid. The opiates tests appeared to perform relatively well with sensitivity results between 69 and 90%. Amphetamines and benzodiazepines tests had lower sensitivity, although the DrugWipe test evaluated was promising for amphetamine. In particular, it is evident that the cannabis and cocaine tests of the devices still lack sensitivity, although further testing of the cocaine tests is desirable due to the low prevalence and low concentrations encountered in this study.
作为欧盟 DRUID 项目的一部分，在比利时、芬兰和荷兰研究了八种现场口服液药物筛选装置的性能。该研究的主要目的是评估这些设备用于测试涉嫌吸毒后驾驶（DUID）的驾驶员的可靠性。通过使用设置在足够低水平的截止值来检测物质的能力来评估设备的性能，从而可以最佳地检测出阳性 DUID 病例。当纳入相关测试时，评估了这些设备对安非他命（s）、大麻、可卡因、阿片类药物和苯二氮䓬类药物的检测能力。由于阳性样本太少，因此未评估一些设备中包含的冰毒、MDMA 和 PCP 测试。将设备结果与口服液中的确认分析结果进行了比较。阿片类药物测试的灵敏度结果在 69%至 90%之间，表现相对较好。安非他命和苯二氮䓬类药物测试的灵敏度较低，尽管评估的 DrugWipe 测试对安非他命有一定的前景。特别值得注意的是，尽管由于本研究中可卡因的低流行率和低浓度，进一步测试可卡因测试是可取的，但这些设备的大麻和可卡因测试仍然缺乏灵敏度。
