Zhang Zhe, Yu Hua, Dong Hui, Wang Li, Jia Ya-Ding, Zhang Su-Hua
Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin 300070, China; Shanxi Eye Hospital, Taiyuan 030002, Shanxi Province, China.
Shanxi Eye Hospital, Taiyuan 030002, Shanxi Province, China.
Int J Ophthalmol. 2016 Feb 18;9(2):230-4. doi: 10.18240/ijo.2016.02.08. eCollection 2016.
To compare the changes in corneal biomechanics measured by ocular response analyzer (ORA) after 2.2-mm microincision cataract surgery and 3.0-mm standard coaxial phacoemulsification.
The prospective nonrandomized study comprised eyes with cataract that had 2.2-mm coaxial microincision or 3.0-mm standard incision phacoemulsification. The corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc) and Goldmann-correlated intraocular pressure (IOPg) were measured by ORA preoperatively and at 1d, 1-, 2-, 3- and 4-week postoperatively. Results were analyzed and compared between groups.
In both groups, CH decreased in the immediate postoperative period (P<0.05), returned to the preoperative level at one week (P=0.249) in the 2.2-mm group, and at two weeks in the 3.0-mm group (P=0.264); there was no significant change in CRF values. In 2.2-mm group, mean IOPcc and IOPg increased at 1d postoperatively (both P<0.05), and returned to preoperative level at one week (P=0.491 and P=0.923, respectively). In 3.0-mm group, mean IOPcc and IOPg increased at 1d and 1wk postoperatively (P=0.005 and P=0.029, respectively), and returned to preoperative level at 2wk (P=0.347 and P=0.887, respectively).
Significant differences between preoperative and postoperative corneal biomechanical values were found for CH, IOPcc and IOPg. But the recovery time courses were different between the two groups. The 2.2-mm coaxial microincision cataract surgery group seemed recovery faster compared to the 3.0-mm standard coaxial phacoemulsification group.
比较2.2毫米微小切口白内障手术和3.0毫米标准同轴超声乳化术后用眼反应分析仪（ORA）测量的角膜生物力学变化。
这项前瞻性非随机研究纳入了接受2.2毫米同轴微小切口或3.0毫米标准切口超声乳化白内障手术的白内障患者。术前以及术后1天、1周、2周、3周和4周用ORA测量角膜滞后（CH）、角膜阻力因子（CRF）、角膜补偿眼压（IOPcc）和Goldmann相关眼压（IOPg）。对两组结果进行分析和比较。
两组患者术后即刻CH均降低（P<0.05），2.2毫米组在术后1周恢复到术前水平（P=0.249），3.0毫米组在术后2周恢复到术前水平（P=0.264）；CRF值无显著变化。2.2毫米组术后1天平均IOPcc和IOPg升高（均P<0.05），1周时恢复到术前水平（分别为P=0.491和P=0.923）。3.0毫米组术后1天和1周平均IOPcc和IOPg升高（分别为P=0.005和P=0.029），2周时恢复到术前水平（分别为P=0.347和P=0.887）。
CH、IOPcc和IOPg的术前和术后角膜生物力学值存在显著差异。但两组的恢复时间进程不同。与3.0毫米标准同轴超声乳化组相比，2.2毫米同轴微小切口白内障手术组似乎恢复得更快。
