约旦糖尿病患者糖尿病视网膜病变的危险因素
Risk Factors for Diabetic Retinopathy among Jordanian Diabetics.
作者信息
Al-Bdour Muawyah D, Al-Till Maha I, Abu Samra Khawla M
机构信息
Department of Ophthalmology, Jordan University Hospital, Amman, Jordan.
出版信息
Middle East Afr J Ophthalmol. 2008 Apr;15(2):77-80. doi: 10.4103/0974-9233.51997.
PURPOSE
To identify the risk factors associated with diabetic retinopathy among diabetic patients at Jordan University Hospital.
METHODS
A total of 986 patients with diabetes mellitus were assessed at Jordan University Hospital. The assessment included detailed relevant history, complete medical and ophthalmic evaluation.
RESULTS
Out of the 1961 eye examined, 64.1 percent had one form of diabetic retinopathy; 54.8 percent had nonproliferative diabetic retinopathy (NPDR), 9.3 percent had proliferative diabetic retinopathy (PDR) and 30.8 percent had maculopathy. Of all participants, 23.5 percent had combined NPDR and maculopathy while 7.6 percent had PDR and maculopathy. Using logistic regression analysis it was shown that old age group, long duration of diabetes, poor glycemic control, uncontrolled blood pressure and the presence of nephropathy were significantly associated with diabetic retinopathy. The incidence of maculopathy was significantly associated with the presence of hypertension, protienuria and high cholesterol level.
CONCLUSION
The challenge for the primary care physician and diabetologist is to attain excellent glycemic control, aggressive control of blood pressure and normalization of blood lipid in order to reduce the risk of blindness and lessen the burden from diabetic retinopathy.
目的
确定约旦大学医院糖尿病患者中与糖尿病视网膜病变相关的危险因素。
方法
约旦大学医院共评估了986例糖尿病患者。评估内容包括详细的相关病史、全面的医学和眼科检查。
结果
在检查的1961只眼中，64.1%患有某种形式的糖尿病视网膜病变；54.8%患有非增殖性糖尿病视网膜病变（NPDR），9.3%患有增殖性糖尿病视网膜病变（PDR），30.8%患有黄斑病变。在所有参与者中，23.5%患有NPDR合并黄斑病变，7.6%患有PDR合并黄斑病变。采用逻辑回归分析表明，老年组、糖尿病病程长、血糖控制差、血压未控制和存在肾病与糖尿病视网膜病变显著相关。黄斑病变的发生率与高血压、蛋白尿和高胆固醇水平显著相关。
结论
初级保健医生和糖尿病专家面临的挑战是实现血糖的良好控制、积极控制血压和血脂正常化，以降低失明风险并减轻糖尿病视网膜病变的负担。
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