Department of Clinical Medicine, Section for Psychiatry, University of Bergen, P. b. 23 Sandviken, 5812 Bergen, Norway.
Eur Arch Psychiatry Clin Neurosci. 2011 Dec;261(8):595-602. doi: 10.1007/s00406-011-0203-9. Epub 2011 Mar 11.
Attention deficit hyperactivity disorder (ADHD) is now recognized as a common disorder both in child and adult psychiatry. Adult patients with a diagnosis of ADHD (n = 572) and community controls (n = 675) responded to auto-questionnaires rating past and present symptoms of ADHD, co-morbid conditions, including migraine, treatment history and work status. The prevalence of migraine was significantly higher in the patient group compared to the controls (28.3% vs. 19.2%, P < 0.001, OR = 1.67, CI 1.28-2.17). The difference from controls was particularly marked for men (22.5% vs. 10.7%, P < 0.001, OR = 2.43, CI 1.51-3.90) but was also significant for women (34.4% vs. 24.9%, P = 0.008, OR = 1.58, CI 1.13-2.21). In both patients and controls, migraine was associated with symptoms of mood and anxiety disorders. These findings point to a co-morbidity of migraine with ADHD, and it is possible that these patients represent a clinical and biological subgroup of adult patients with ADHD.
注意缺陷多动障碍（ADHD）现在被认为是儿童和成人精神病学中的常见疾病。诊断为 ADHD 的成年患者（n=572）和社区对照者（n=675）对自评问卷进行了回答，问卷评估了 ADHD 的过去和现在的症状、合并症，包括偏头痛、治疗史和工作状况。与对照组相比，患者组偏头痛的患病率显著更高（28.3%比 19.2%，P<0.001，OR=1.67，CI 1.28-2.17）。与对照组相比，这种差异在男性中尤为明显（22.5%比 10.7%，P<0.001，OR=2.43，CI 1.51-3.90），但在女性中也有显著差异（34.4%比 24.9%，P=0.008，OR=1.58，CI 1.13-2.21）。在患者和对照组中，偏头痛都与情绪和焦虑障碍的症状有关。这些发现表明偏头痛与 ADHD 存在合并症，这些患者可能代表了 ADHD 成年患者的一个临床和生物学亚组。
