Department of Dermatology, Charité - Universitätsmedizin Berlin, Center of Experimental and Applied Cutaneous Physiology (CCP), Berlin, Germany.
Skin Pharmacol Physiol. 2011;24(5):238-44. doi: 10.1159/000326074. Epub 2011 Mar 27.
Environmental factors like air pollutants, radiation of the sun and stress factors such as illness, smoking, or alcohol abuse produce free radicals in the human tissue as well as in the skin. Free radicals serve as the main cause for premature skin aging. Additionally, they also contribute towards immunosuppression and the formation of skin diseases including cancer. The human organism has developed a protection system against the destructive action of free radicals by means of the antioxidant network. In the present study, the interaction of free radicals and carotenoid antioxidants in the human skin under in vivo conditions was investigated and summarized. The measurement of carotenoids in human skin was performed in vivo using resonance Raman spectroscopy.
环境因素，如空气污染物、太阳辐射以及疾病、吸烟或酗酒等压力因素，会在人体组织和皮肤中产生自由基。自由基是导致皮肤过早衰老的主要原因。此外，它们还会导致免疫抑制以及包括癌症在内的皮肤病的形成。人类机体通过抗氧化网络系统来对抗自由基的破坏作用。本研究调查并总结了人类皮肤在体内条件下自由基与类胡萝卜素抗氧化剂的相互作用。采用共振拉曼光谱法在体测量了人类皮肤中的类胡萝卜素。
