铜催化的芳基和乙烯基硼酸与亲电三氟甲基化试剂的三氟甲基化反应。
Copper-catalyzed trifluoromethylation of aryl and vinyl boronic acids with an electrophilic trifluoromethylating reagent.
机构信息
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, People's Republic of China.
出版信息
Org Lett. 2011 May 6;13(9):2342-5. doi: 10.1021/ol2005903. Epub 2011 Apr 7.
PMID:21473568
Abstract
A copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with Togni's reagent was described. The reaction proceeded in good to excellent yields for a range of different substrates including heteroarylboronic acids and substrates with a variety of functional groups under mild reaction conditions.
摘要
本文描述了 Togni 试剂促进的芳基和烯基硼酸的铜催化三氟甲基化反应。在温和的反应条件下，该反应对于一系列不同的底物（包括杂芳基硼酸和具有各种官能团的底物）具有良好到优秀的产率。
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