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肤得安中药软膏与1%磺胺嘧啶银乳膏两种换药方法对Ⅱ度烧伤创面愈合时间的比较

Comparison of healing time of the 2 degree burn wounds with two dressing methods of fundermol herbal ointment and 1% silver sulfadiazine cream.

作者信息

Daryabeigi Reza, Heidari Mohammad, Hosseini Sayed Abbas, Omranifar Mahmoud

机构信息

Department of Medical Surgical Nursing, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Iran J Nurs Midwifery Res. 2010 Summer;15(3):97-101.

PMID:21589770
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3093171/
Abstract

BACKGROUND

Burn wounds are one of the health problems in modern societies that are associated with irreparable harms and many side problems for patients and their families. Infection due to burn wounds is the main cause of death in such patients. One of the methods to prevent infection of burn wounds is topical antibiotic ointments. This study aimed to investigate and identify effective ointments to treat burn wounds. For this purpose, the effects of two types of ointment, fundermol and 1% silver sulfadiazine cream on second degree burn wounds were compared.

METHODS

This was a clinical trial study conducted in 2008. Using convenient and continuous sampling method, 50 patients referred to Imam Mousa Kazem Burn Injury Clinic in Isfahan, Iran with 2(nd) degree burn wounds in 1% to 10% surface area were enrolled. The patients were randomly divided into two groups of treatment with fundermol and sulfadiazine and the dressing was changed once a day. The healing time for burn wounds in each patient was recorded in a checklist and data were analyzed by independent t-test via SPSS software.

RESULTS

The healing time of burn wounds in the group treated with fundermol was shorter than that in the group treated with sulfadiazine (p < 0.001).

CONCLUSIONS

The present study showed that fundermol ointment accelerates burn wound healing. Therefore, fundermol can be introduced as a good replacement for current treatments of burn wounds.

摘要

背景

烧伤创面是现代社会中的健康问题之一,会给患者及其家庭带来无法弥补的伤害和诸多附带问题。烧伤创面感染是此类患者死亡的主要原因。预防烧伤创面感染的方法之一是外用抗生素软膏。本研究旨在调查和确定治疗烧伤创面的有效软膏。为此,比较了两种软膏,即肤轻松软膏和1%磺胺嘧啶银乳膏对二度烧伤创面的效果。

方法

这是一项于2008年进行的临床试验研究。采用便利连续抽样法,纳入了50名转诊至伊朗伊斯法罕伊玛目穆萨·卡泽姆烧伤诊所、烧伤面积为1%至10%的二度烧伤患者。患者被随机分为肤轻松治疗组和磺胺嘧啶治疗组,每天更换一次敷料。在检查表中记录每位患者烧伤创面的愈合时间,并通过SPSS软件用独立t检验分析数据。

结果

肤轻松治疗组烧伤创面的愈合时间短于磺胺嘧啶治疗组(p < 0.001)。

结论

本研究表明肤轻松软膏可加速烧伤创面愈合。因此,肤轻松可作为烧伤创面现有治疗方法的良好替代品。

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本文引用的文献

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Burns. 2007 Dec;33(8):958-65. doi: 10.1016/j.burns.2007.05.002. Epub 2007 Sep 14.
2
Comparison between Alpha and silver sulfadiazine ointments in treatment of Pseudomonas infections in 3rd degree burns.磺胺嘧啶银软膏与α软膏治疗三度烧伤铜绿假单胞菌感染的比较
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Infections in burn patients--experience in a tertiary care hospital.烧伤患者的感染——一家三级护理医院的经验
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An in vitro study of the anti-microbial efficacy of a 1% silver sulphadiazine and 0.2% chlorhexidine digluconate cream, 1% silver sulphadiazine cream and a silver coated dressing.一项关于1%磺胺嘧啶银和0.2%葡萄糖酸氯己定乳膏、1%磺胺嘧啶银乳膏及银涂层敷料抗菌效果的体外研究。
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