三十年的多序列码。
Thirty years of multiple sequence codes.
机构信息
Genome Diversity Center, Institute of Evolution, University of Haifa, Haifa, Israel.
出版信息
Genomics Proteomics Bioinformatics. 2011 Apr;9(1-2):1-6. doi: 10.1016/S1672-0229(11)60001-6.
Abstract
An overview is presented on the status of studies on multiple codes in genetic sequences. Indirectly, the existence of multiple codes is recognized in the form of several rediscoveries of Second Genetic Code that is different each time. A due credit is given to earlier seminal work related to the codes often neglected in literature. The latest developments in the field of chromatin code are discussed, as well as perspectives of single-base resolution studies of nucleosome positioning, including rotational setting of DNA on the surface of the histone octamers.
摘要
本文概述了遗传序列中多码研究的现状。间接的，通过多次重新发现每次都不同的第二遗传密码，人们认识到了多码的存在。早期与代码相关的开创性工作经常在文献中被忽视，本文对这些工作给予了应有的肯定。本文还讨论了染色质密码领域的最新进展，以及单碱基分辨率研究核小体定位的前景，包括 DNA 在组蛋白八聚体表面的旋转设置。
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本文引用的文献
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Single-base resolution nucleosome mapping on DNA sequences.单碱基分辨率核小体在 DNA 序列上的作图。
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