金纳米粒子在癌症治疗中的应用。
Gold nanoparticles in cancer therapy.
机构信息
Department of Anatomy, National University of Singapore, Singapore.
出版信息
Acta Pharmacol Sin. 2011 Aug;32(8):983-90. doi: 10.1038/aps.2011.82. Epub 2011 Jul 11.
Abstract
The rapid advancement of nanotechnology in recent years has fuelled a burgeoning interest in the field of nanoparticle research, in particular, its application in the medical arena. A constantly expanding knowledge based on a better understanding of the properties of gold nanoparticles (AuNPs) coupled with relentless experimentation means that the frontiers of nanotechnology are constantly being challenged. At present, there seems to be heightened interest in the application of AuNPs to the management of cancer, encompassing diagnosis, monitoring and treatment of the disease. These efforts are undertaken in the hope of revolutionizing current methods of treatment and treatment strategies for a multifactorial disease such as cancer. This review will focus on the current applications of AuNPs in cancer management.
摘要
近年来，纳米技术的快速发展激发了人们对纳米颗粒研究领域的浓厚兴趣，特别是其在医学领域的应用。基于对金纳米粒子（AuNPs）特性更好理解的不断扩展的知识，再加上不懈的实验，意味着纳米技术的前沿正在不断受到挑战。目前，人们似乎对将 AuNPs 应用于癌症的管理越来越感兴趣，包括癌症的诊断、监测和治疗。这些努力的目的是希望彻底改变癌症等多因素疾病的当前治疗方法和治疗策略。本综述将重点介绍 AuNPs 在癌症管理中的当前应用。
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