Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany.
BMC Public Health. 2011 Jul 20;11:579. doi: 10.1186/1471-2458-11-579.
To identify factors which determine high life satisfaction (LS) and to analyse the prognostic influence of LS on mortality.
Data collection was conducted on 2,675 participants, age 25-74 years, as part of the MONICA Augsburg Project 1994-95. Multivariate logistic regression analyses were used to determine factors associated with high LS (measured with one item, 6-level Likert scale, where "high" = very satisfied/most of the time very satisfied with ones personal life). After 12 years mean follow-up, a total of 245 deaths occurred. We calculated age- and sex-adjusted incident mortality rates per 10,000. Hazard ratios (HRs) were estimated from Cox proportional hazards models.
Independent determinants of LS were income, health-perception, and social support, as well as somatisation, anger or depressive symptoms (all p < 0.05). Participants with higher LS (n = 721, 27%) benefited the most with respect to absolute mortality risk reduction (higher LS = 67; mid = 98; low = 140 per 10,000). The sex-stratified analyses indicated an independent association of higher LS and survival for men (HR 0.55; 95% CI 0.37 - 0.81) but not for women.
Baseline assessment demonstrated that psychological, social and life-style factors, but not somatic co-morbidities, were relevant determinants of LS. Moreover, the analysis showed that men with higher LS have a substantial long-term survival benefit. The observed association between LS and mortality may be attributed to common underlying causes such as social network integration and/or self-rated health.
确定决定高生活满意度（LS）的因素，并分析 LS 对死亡率的预后影响。
数据采集是在 1994-95 年 MONICA Augsburg 项目中，对 2675 名年龄在 25-74 岁的参与者进行的。使用多变量逻辑回归分析来确定与高 LS（通过一项 6 级李克特量表衡量，“高”=对个人生活非常满意/大部分时间非常满意）相关的因素。在 12 年的平均随访后，共有 245 人死亡。我们计算了每 10000 人年龄和性别调整后的发病率。使用 Cox 比例风险模型估计风险比（HRs）。
LS 的独立决定因素是收入、健康感知和社会支持，以及躯体化、愤怒或抑郁症状（均<0.05）。LS 较高的参与者（n=721，27%）在绝对死亡率降低方面获益最大（LS 较高=67；中值=98；低=140/10000）。性别分层分析表明，LS 较高与男性生存独立相关（HR 0.55；95%CI 0.37-0.81），但与女性无关。
基线评估表明，心理、社会和生活方式因素，而不是躯体合并症，是 LS 的相关决定因素。此外，分析表明，LS 较高的男性具有实质性的长期生存获益。LS 与死亡率之间的观察到的关联可能归因于共同的潜在原因，例如社交网络融合和/或自我评估的健康状况。
