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本文引用的文献

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Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic Variability.传统医学到现代药物基因组学:阿育吠陀体质类型和 CYP2C19 基因多态性与代谢变异性相关。
Evid Based Complement Alternat Med. 2011;2011:249528. doi: 10.1093/ecam/nep206. Epub 2011 Jun 8.
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Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome.用于治疗特发性慢性疲劳和慢性疲劳综合征的传统中草药。
Cochrane Database Syst Rev. 2009 Oct 7(4):CD006348. doi: 10.1002/14651858.CD006348.pub2.
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Origins and functional impact of copy number variation in the human genome.人类基因组中拷贝数变异的起源和功能影响。
Nature. 2010 Apr 1;464(7289):704-12. doi: 10.1038/nature08516. Epub 2009 Oct 7.
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Sasang constitution as a risk factor for diabetes mellitus: a cross-sectional study.作为糖尿病发病风险因素的体质类型:一项横断面研究。
Evid Based Complement Alternat Med. 2009 Sep;6 Suppl 1(Suppl 1):99-103. doi: 10.1093/ecam/nep054.
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Association between Genetic Polymorphism of Multidrug Resistance 1 Gene and Sasang Constitutions.多药耐药 1 基因遗传多态性与四象体质的关系。
Evid Based Complement Alternat Med. 2009 Sep;6 Suppl 1(Suppl 1):73-80. doi: 10.1093/ecam/nep118.
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Genetic approach to elucidation of sasang constitutional medicine.从遗传学角度阐明四象体质医学。
Evid Based Complement Alternat Med. 2009 Sep;6 Suppl 1(Suppl 1):51-7. doi: 10.1093/ecam/nep058.
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Improving insulin resistance with traditional Chinese medicine in type 2 diabetic patients.运用中药改善2型糖尿病患者的胰岛素抵抗
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[Progress on prevention and treatment of Chinese medicine to molecular mechanism of liver cancer].[中医药防治肝癌分子机制研究进展]
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A genome-wide scan for the Sasang constitution in a Korean family suggests significant linkage at chromosomes 8q11.22-23 and 11q22.1-3.对一个韩国家庭的体质类型进行全基因组扫描,结果表明在8号染色体的q11.22 - 23区域和11号染色体的q22.1 - 3区域存在显著连锁。
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Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward?受传统医学启发的药物发现方法:阿育吠陀医学能指明前进的方向吗?
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传统医学与基因组学。

Traditional medicine and genomics.

作者信息

Joshi Kalpana, Ghodke Yogita, Shintre Pooja

机构信息

Department of Biotechnology, Sinhagad College of Engineering, Pune, India.

出版信息

J Ayurveda Integr Med. 2010 Jan;1(1):26-32. doi: 10.4103/0975-9476.59824.

DOI:10.4103/0975-9476.59824
PMID:21829298
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3149388/
Abstract

'Omics' developments in the form of genomics, proteomics and metabolomics have increased the impetus of traditional medicine research. Studies exploring the genomic, proteomic and metabolomic basis of human constitutional types based on Ayurveda and other systems of oriental medicine are becoming popular. Such studies remain important to developing better understanding of human variations and individual differences. Countries like India, Korea, China and Japan are investing in research on evidence-based traditional medicines and scientific validation of fundamental principles. This review provides an account of studies addressing relationships between traditional medicine and genomics.

摘要

以基因组学、蛋白质组学和代谢组学形式出现的“组学”发展,增强了传统医学研究的动力。基于阿育吠陀和其他东方医学体系探索人类体质类型的基因组学、蛋白质组学和代谢组学基础的研究正变得越来越普遍。这类研究对于更好地理解人类变异和个体差异仍然很重要。印度、韩国、中国和日本等国家正在投资开展循证传统医学研究以及对基本原理进行科学验证。本综述介绍了有关传统医学与基因组学之间关系的研究情况。