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斑秃:一种新的治疗方案。

Alopecia areata: a new treatment plan.

机构信息

Department of Dermatology, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia.

出版信息

Clin Cosmet Investig Dermatol. 2011;4:107-15. doi: 10.2147/CCID.S22767. Epub 2011 Jul 22.

DOI:10.2147/CCID.S22767
PMID:21833161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3149478/
Abstract

Many therapeutic modalities have been used to treat alopecia areata, with variable efficacy and safety profiles. Unfortunately, none of these agents is curative or preventive. Also, many of these therapeutic agents have not been subjected to randomized, controlled trials, and, except for topical immunotherapy, there are few published studies on long-term outcomes. The treatment plan is designed according to the patient's age and extent of disease. In this paper, the therapeutic agents are organized according to their efficacy and safety profiles into first-line, second-line, and third-line options.

摘要

许多治疗方法已被用于治疗斑秃,疗效和安全性各不相同。遗憾的是,这些药物均无根治或预防作用。此外,许多治疗药物尚未经过随机对照试验,除了局部免疫疗法外,关于长期疗效的研究也很少。治疗方案是根据患者的年龄和疾病程度设计的。本文根据疗效和安全性将治疗药物分为一线、二线和三线选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e374/3149478/16430badcb67/ccid-4-107f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e374/3149478/16430badcb67/ccid-4-107f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e374/3149478/16430badcb67/ccid-4-107f1.jpg

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Dermatol Ther (Heidelb). 2025 May 5. doi: 10.1007/s13555-025-01421-2.
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Sexual Dysfunction in Alopecia Areata: A Systematic Review.斑秃中的性功能障碍:一项系统评价。

本文引用的文献

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Bimatoprost in the treatment of eyelash universalis alopecia areata.比马前列素治疗全秃型斑秃。
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Hair regrowth with topical triiodothyronine ointment in patients with alopecia areata: a double-blind, randomized pilot clinical trial of efficacy.三碘甲状腺原氨酸软膏局部治疗斑秃患者的毛发生长:疗效的双盲、随机临床试验。
J Eur Acad Dermatol Venereol. 2012 May;26(5):654-6. doi: 10.1111/j.1468-3083.2011.04088.x. Epub 2011 Apr 27.
3
Efficacy and tolerability of methotrexate in severe childhood alopecia areata.
J Clin Med. 2025 Apr 10;14(8):2602. doi: 10.3390/jcm14082602.
4
Safety and Efficacy of Ritlecitinib for the Treatment of Patients with Alopecia Areata: A Systematic Review and Meta-Analysis of Controlled Trials.利特昔替尼治疗斑秃患者的安全性和有效性:一项对照试验的系统评价和荟萃分析
J Clin Med. 2025 Mar 8;14(6):1817. doi: 10.3390/jcm14061817.
5
"Hair is your crown and glory" - Black women's experiences of living with alopecia and the role of social support.“头发是你的王冠与荣耀”——黑人女性斑秃患者的生活经历及社会支持的作用
Health Psychol Rep. 2024 Jan 26;12(2):154-165. doi: 10.5114/hpr/177730. eCollection 2024.
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A diagnostic clue: New onset alopecia sparing white hairs.一个诊断线索:新发脱发,白发未受影响。
JAAD Case Rep. 2023 Dec 16;44:107-109. doi: 10.1016/j.jdcr.2023.11.030. eCollection 2024 Feb.
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The Efficacy and Adverse Effects of Corticosteroid Pulse Therapy in Alopecia Areata: A Review Article.糖皮质激素冲击疗法治疗斑秃的疗效与不良反应:一篇综述文章
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Survey of pediatric dermatologist views on treatment for alopecia areata.儿科皮肤科医生对斑秃治疗观点的调查。
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Alopecia Areata: Current Treatments and New Directions.斑秃:现有治疗方法和新方向。
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[Treatment of alopecia areata with prednisone in a once-monthly oral pulse].[每月一次口服脉冲式泼尼松治疗斑秃]
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[Long-term follow-up of the efficacy of methotrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia areata totalis or universalis].甲氨蝶呤单药或联合低剂量口服糖皮质激素治疗全秃或普秃疗效的长期随访
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