Department of Environmental Systems Engineering, Kochi University of Technology, 185 Miyanokuchi, Tosayamada, Kami, Kochi 782-8502, Japan.
Evid Based Complement Alternat Med. 2011;2011:670349. doi: 10.1155/2011/670349. Epub 2011 Sep 26.
Research into natural products from the marine environment, including microorganisms, has rapidly increased over the past two decades. Despite the enormous difficulty in isolating and harvesting marine bacteria, microbial metabolites are increasingly attractive to science because of their broad-ranging pharmacological activities, especially those with unique color pigments. This current review paper gives an overview of the pigmented natural compounds isolated from bacteria of marine origin, based on accumulated data in the literature. We review the biological activities of marine compounds, including recent advances in the study of pharmacological effects and other commercial applications, in addition to the biosynthesis and physiological roles of associated pigments. Chemical structures of the bioactive compounds discussed are also presented.
在过去的二十年中，对海洋环境中天然产物的研究，包括微生物，迅速增加。尽管从海洋中分离和收获细菌极具挑战性，但由于微生物代谢产物具有广泛的药理活性，尤其是那些具有独特颜色色素的代谢产物，它们对科学界越来越有吸引力。本综述论文根据文献中积累的数据，概述了从海洋来源的细菌中分离出的有色天然化合物。我们综述了海洋化合物的生物活性，包括在药理作用研究和其他商业应用方面的最新进展，以及相关色素的生物合成和生理作用。所讨论的生物活性化合物的化学结构也一并呈现。
