School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.
Nat Rev Microbiol. 2011 Oct 11;9(12):849-59. doi: 10.1038/nrmicro2653.
The compatible solute dimethylsulphoniopropionate (DMSP) has important roles in marine environments. It is an anti-stress compound made by many single-celled plankton, some seaweeds and a few land plants that live by the shore. Furthermore, in the oceans it is a major source of carbon and sulphur for marine bacteria that break it down to products such as dimethyl sulphide, which are important in their own right and have wide-ranging effects, from altering animal behaviour to seeding cloud formation. In this Review, we describe how recent genetic and genomic work on the ways in which several different bacteria, and some fungi, catabolize DMSP has provided new and surprising insights into the mechanisms, regulation and possible evolution of DMSP catabolism in microorganisms.
相容溶质二甲亚砜丙酸盐（DMSP）在海洋环境中具有重要作用。它是许多单细胞浮游生物、一些海藻和一些生活在海岸边的陆地植物制造的一种抗应激化合物。此外，在海洋中，它是海洋细菌将其分解为二甲基硫等产物的主要碳源和硫源，这些产物本身很重要，对动物行为的改变到云的形成等方面都有广泛的影响。在这篇综述中，我们描述了最近关于几种不同细菌和一些真菌代谢 DMSP 的遗传和基因组研究，为微生物中 DMSP 代谢的机制、调控和可能的进化提供了新的、令人惊讶的见解。
