一氧化氮是一种激素吗？
Is nitric oxide a hormone?
作者信息
Ghasemi Asghar, Zahediasl Saleh
机构信息
Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Iran Biomed J. 2011;15(3):59-65.
Abstract
Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this review is considering available literature on endocrine roles of NO and/or its metabolites, i.e. nitrite and nitrate. Existing data suggest the idea that NO is a hormone that after production in tissues, it is stabilized and transported as nitrite and/or S-nitrosothiols in the blood to target cells.
摘要
一氧化氮（NO）是一种简单且广泛存在的信号分子，在几乎每个生物系统中都发挥着重要作用。最近的证据表明，NO可能作为一种内分泌分子发挥作用。本综述的目的是考虑关于NO及其代谢产物（即亚硝酸盐和硝酸盐）内分泌作用的现有文献。现有数据表明，NO是一种激素，在组织中产生后，它以亚硝酸盐和/或S-亚硝基硫醇的形式在血液中稳定并运输到靶细胞。
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