Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy.
Nutrition. 2012 Jan;28(1):108-11. doi: 10.1016/j.nut.2011.07.005. Epub 2011 Oct 12.
D-Lactic acidosis is a rare complication that occurs in patients with short bowel syndrome due to surgical intestine resection for treatment of obesity. The clinical presentation is characterized by neurologic symptoms and high anion gap metabolic acidosis. The incidence of this syndrome is unknown, probably because of misdiagnosis and sometimes symptoms may be incorrectly attributed to other causes. Therapy is based on low carbohydrate diet, sodium bicarbonate intravenous, rehydratation, antiobiotics, and probiotics that only produce L-lactate. In the case we describe, D-lactic acidosis encephalopathy occurred 25 y after bypass jejunoileal, due to Salmonella enteriditis infection.
D-乳酸酸中毒是一种罕见的并发症，发生于因肥胖症接受外科肠道切除术治疗的短肠综合征患者。其临床表现为神经症状和高阴离子间隙代谢性酸中毒。该综合征的发病率尚不清楚，可能是由于误诊，而且有时症状可能被错误地归因于其他原因。治疗基于低碳水化合物饮食、静脉内碳酸氢钠、补液、抗生素和仅产生 L-乳酸的益生菌。在我们描述的病例中，由于沙门氏菌肠炎感染，旁路空肠回肠术后 25 年发生 D-乳酸酸中毒性脑病。
