• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

分层皮片供皮区创面处理的随机对照研究:比较聚氨酯敷料与藻酸钙敷料的疗效。

Split-thickness skin graft donor site management: a randomized controlled trial comparing polyurethane with calcium alginate dressings.

机构信息

Victorian Adult Burns Service, The Alfred Hospital, Commercial Road, Melbourne, Victoria, Australia.

出版信息

Int Wound J. 2012 Apr;9(2):126-31. doi: 10.1111/j.1742-481X.2011.00867.x. Epub 2011 Nov 4.

DOI:10.1111/j.1742-481X.2011.00867.x
PMID:22051247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7950605/
Abstract

Split-thickness skin grafting (SSG) is a common reconstructive technique for the treatment of patients with deep burns and other traumatic injuries. The management of the donor site after harvesting an SSG remains controversial because of a variety of dressings available for use. The aim of this randomized controlled trial was to compare the effectiveness of a polyurethane dressing, Allevyn™, to a calcium alginate, Kaltostat®. From August 2009 to April 2010, 36 patients were randomized to Allevyn™ or Kaltostat® for donor site management following split skin graft surgery. Pain intensity and adverse events were the primary outcomes assessed. Secondary outcome measures included time for wound healing, ease of application and removal and overall patient satisfaction. Time to first dressing change was earlier in those randomized to Allevyn™ compared with Kaltostat® (5·5 days versus 8·11 days, P = 0·014). In patients randomized to Allevyn™, excessive exudate lead to a significantly increased number of dressing changes before day 10 (14 days versus 7 days, P = 0·018). The total number of dressing changes applied was also greater in those with Allevyn™ compared with Kaltstat® (P = 0·007). There were no significant differences between the two treatment groups with respect to time to wound healing, level of pain intensity, length of stay, staff and patient satisfaction levels. This trial showed Allevyn™ to be associated with increase demands on nursing time, increased cost of dressing products, medical consumables and wastes. Kaltostat® remains the dressing of choice for initial donor site dressing in this burns unit.

摘要

分层皮片移植(SSG)是治疗深度烧伤和其他创伤患者的常用重建技术。由于有多种可供选择的敷料,因此对于 SSG 供体部位的处理仍存在争议。本随机对照试验旨在比较聚氨酯敷料 Allevyn™与藻酸钙敷料 Kaltostat®在 SSG 供体部位管理中的有效性。

2009 年 8 月至 2010 年 4 月,36 例患者随机分为 Allevyn™组或 Kaltostat®组,用于 SSG 术后供体部位管理。主要评估指标为疼痛强度和不良事件。次要评估指标包括伤口愈合时间、应用和去除的便利性以及总体患者满意度。

与 Kaltostat®组相比,随机分配到 Allevyn™组的患者首次更换敷料的时间更早(5.5 天比 8.11 天,P = 0.014)。在随机分配到 Allevyn™的患者中,过多的渗出物导致在第 10 天之前需要更换更多的敷料(14 天比 7 天,P = 0.018)。与 Kaltostat®组相比,Allevyn™组应用的敷料总数也更多(P = 0.007)。

两组在伤口愈合时间、疼痛强度水平、住院时间、工作人员和患者满意度方面无显著差异。本试验表明,Allevyn™会增加护理时间的需求,增加敷料产品、医疗耗材和废物的成本。在本烧伤单位中,Kaltostat®仍然是初始供体部位敷料的首选。

相似文献

1
Split-thickness skin graft donor site management: a randomized controlled trial comparing polyurethane with calcium alginate dressings.分层皮片供皮区创面处理的随机对照研究:比较聚氨酯敷料与藻酸钙敷料的疗效。
Int Wound J. 2012 Apr;9(2):126-31. doi: 10.1111/j.1742-481X.2011.00867.x. Epub 2011 Nov 4.
2
Alginate dressing and polyurethane film versus paraffin gauze in the treatment of split-thickness skin graft donor sites: a randomized controlled pilot study.藻酸盐敷料与聚氨酯薄膜和凡士林纱布在处理供皮区的比较:一项随机对照的初步研究。
Adv Skin Wound Care. 2013 Feb;26(2):67-73. doi: 10.1097/01.ASW.0000426715.57540.8d.
3
Split-thickness skin graft donor sites: a comparative study of two absorbent dressings.中厚皮片供皮区:两种吸水性敷料的比较研究
J Wound Care. 2007 Nov;16(10):433-8. doi: 10.12968/jowc.2007.16.10.27912.
4
Management of split-thickness skin graft donor sites: a randomized controlled trial of calcium alginate versus polyurethane film dressing.分层皮片供皮区处理的随机对照研究:藻酸钙与聚氨酯薄膜敷料的比较。
Dermatology. 2013;227(4):361-6. doi: 10.1159/000356122. Epub 2013 Nov 20.
5
Management of pediatric skin-graft donor sites: a randomized controlled trial of three wound care products.小儿皮肤移植供区的管理:三种伤口护理产品的随机对照试验
J Burn Care Res. 2015 Jan-Feb;36(1):159-66. doi: 10.1097/BCR.0000000000000161.
6
Clinical effectiveness of alginate silver dressing in outpatient management of partial-thickness burns.藻酸盐银敷料在门诊部分厚度烧伤处理中的临床效果。
Int Wound J. 2010 Dec;7(6):467-71. doi: 10.1111/j.1742-481X.2010.00718.x. Epub 2010 Sep 21.
7
Clinical trial comparing 3 different wound dressings for the management of partial-thickness skin graft donor sites.比较三种不同创面敷贴在处理部分厚度皮肤移植供区创面的临床试验。
J Wound Ostomy Continence Nurs. 2011 Nov-Dec;38(6):643-7. doi: 10.1097/WON.0b013e3182349d2f.
8
Comparison of hydrocellular foam and calcium alginate in the healing and comfort of split-thickness skin-graft donor sites.水细胞泡沫敷料与海藻酸钙敷料在中厚皮片供皮区愈合及舒适度方面的比较。
J Wound Care. 2001 Jul;10(7):289-91. doi: 10.12968/jowc.2001.10.7.26347.
9
The use of modern dressings in managing split-thickness skin graft donor sites: a single-centre randomised controlled trial.现代敷料在处理中厚皮片供皮区的应用:一项单中心随机对照试验。
J Wound Care. 2017 Jun 2;26(6):281-291. doi: 10.12968/jowc.2017.26.6.281.
10
Split-thickness skin graft donor site management. A randomized prospective trial comparing a hydrophilic polyurethane absorbent foam dressing with a petrolatum gauze dressing.断层皮片供皮区的处理。一项比较亲水性聚氨酯吸收性泡沫敷料与凡士林纱布敷料的随机前瞻性试验。
Arch Otolaryngol Head Neck Surg. 1995 Oct;121(10):1145-9. doi: 10.1001/archotol.1995.01890100055009.

引用本文的文献

1
Evaluating the therapeutic efficacy and safety of alginate-based dressings in burn wound and donor site wound management associated with burn surgery: a systematic review and meta-analysis of contemporary randomized controlled trials.评估藻酸盐敷料在烧伤创面及烧伤手术相关供皮区创面处理中的治疗效果和安全性:当代随机对照试验的系统评价和荟萃分析。
BMC Surg. 2025 May 16;25(1):215. doi: 10.1186/s12893-025-02956-z.
2
Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study.用于治疗渗出性伤口的商用伤口敷料:一项深入的物理化学对比研究。
Burns Trauma. 2022 Jun 21;10:tkac024. doi: 10.1093/burnst/tkac024. eCollection 2022.
3
Polyurethane Versus Calcium Alginate Dressings for Split-Thickness Skin Graft Donor Site: A Systematic Review and Meta-Analysis.用于中厚皮片供皮区的聚氨酯与藻酸钙敷料:一项系统评价和Meta分析
Cureus. 2021 Nov 30;13(11):e20027. doi: 10.7759/cureus.20027. eCollection 2021 Nov.
4
Selection of Appropriate Wound Dressing for Various Wounds.为各类伤口选择合适的伤口敷料。
Front Bioeng Biotechnol. 2020 Mar 19;8:182. doi: 10.3389/fbioe.2020.00182. eCollection 2020.
5
Human Amniotic Membrane: A New Option for Graft Donor Sites - Systematic Review and Meta-analysis.人羊膜:一种新的移植物供体部位选择——系统评价和荟萃分析。
Int Wound J. 2020 Jun;17(3):547-554. doi: 10.1111/iwj.13313. Epub 2020 Jan 23.
6
Comparison of the efficacy and safety of povidone-iodine foam dressing (Betafoam), hydrocellular foam dressing (Allevyn), and petrolatum gauze for split-thickness skin graft donor site dressing.比较聚维酮碘泡沫敷料(Betafoam)、水胶体泡沫敷料(Allevyn)和凡士林纱布在供皮区创面的疗效和安全性。
Int Wound J. 2019 Apr;16(2):379-386. doi: 10.1111/iwj.13043. Epub 2018 Nov 26.
7
Comparative study on the donor site aesthetic outcome between epidermal graft and split-thickness skin graft.表皮移植与断层皮片移植供区美学效果的比较研究。
Int Wound J. 2019 Apr;16(2):354-359. doi: 10.1111/iwj.13039. Epub 2018 Nov 15.
8
An evidence-based review of split-thickness skin graft donor site dressings.分层皮片供皮区敷料的循证评价
Int Wound J. 2018 Dec;15(6):1000-1009. doi: 10.1111/iwj.12967. Epub 2018 Aug 17.
9
Effectiveness of collagen/oxidised regenerated cellulose/silver-containing composite wound dressing for the treatment of medium-depth split-thickness skin graft donor site wounds in multi-morbid patients: a prospective, non-comparative, single-centre study.胶原/氧化再生纤维素/含银复合创伤敷料治疗多合并症患者中厚层断层皮片供皮区创面的有效性:一项前瞻性、非对照、单中心研究。
Int Wound J. 2017 Oct;14(5):791-800. doi: 10.1111/iwj.12698. Epub 2016 Dec 1.
10
Back Grafting the Split-Thickness Skin Graft Donor Site.回植中厚皮片供皮区。
J Burn Care Res. 2017 Jan/Feb;38(1):e443-e449. doi: 10.1097/BCR.0000000000000314.

本文引用的文献

1
Management of split-thickness skin graft donor site: a prospective clinical trial for comparison of five different dressing materials.分层皮片供皮区的处理:五种不同敷贴材料的前瞻性临床对比研究。
Burns. 2010 Nov;36(7):999-1005. doi: 10.1016/j.burns.2009.05.017. Epub 2010 Apr 9.
2
Hydrofiber dressing with silver for the management of split-thickness donor sites: a randomized evaluation of two protocols of care.水胶体银敷料在处理供皮区的应用:两种护理方案的随机评估。
Burns. 2010 Aug;36(5):665-72. doi: 10.1016/j.burns.2009.06.193. Epub 2009 Dec 6.
3
Systematic review of skin graft donor-site dressings.系统评价皮肤移植供皮区敷料。
Plast Reconstr Surg. 2009 Jul;124(1):298-306. doi: 10.1097/PRS.0b013e3181a8072f.
4
Split-thickness skin graft donor sites: a comparative study of two absorbent dressings.中厚皮片供皮区:两种吸水性敷料的比较研究
J Wound Care. 2007 Nov;16(10):433-8. doi: 10.12968/jowc.2007.16.10.27912.
5
Acticoat versus Allevyn as a split-thickness skin graft donor-site dressing: a prospective comparative study.Acticoat与爱立肤用于中厚皮片供皮区敷料的前瞻性对比研究。
Ann Plast Surg. 2007 Oct;59(4):415-22. doi: 10.1097/SAP.0b013e3180312705.
6
Randomized clinical study of Hydrofiber dressing with silver or silver sulfadiazine in the management of partial-thickness burns.含银水凝胶敷料与磺胺嘧啶银治疗浅Ⅱ度烧伤的随机临床研究
J Burn Care Res. 2006 May-Jun;27(3):298-309. doi: 10.1097/01.BCR.0000216741.21433.66.
7
Core outcome measures for chronic pain clinical trials: IMMPACT recommendations.慢性疼痛临床试验的核心结局指标:IMMPACT 建议
Pain. 2005 Jan;113(1-2):9-19. doi: 10.1016/j.pain.2004.09.012.
8
Comparison of hydrocellular foam and calcium alginate in the healing and comfort of split-thickness skin-graft donor sites.水细胞泡沫敷料与海藻酸钙敷料在中厚皮片供皮区愈合及舒适度方面的比较。
J Wound Care. 2001 Jul;10(7):289-91. doi: 10.12968/jowc.2001.10.7.26347.
9
Which dressing for split-thickness skin graft donor sites?哪种敷料适用于中厚皮片供区?
Ann Plast Surg. 2001 Apr;46(4):409-14. doi: 10.1097/00000637-200104000-00010.
10
Evaluation of a combined calcium sodium alginate and bio-occlusive membrane dressing in the management of split-thickness skin graft donor sites.海藻酸钙钠与生物封闭膜联合敷料用于中厚皮片供皮区处理的评估
Ann Plast Surg. 2001 Apr;46(4):405-8. doi: 10.1097/00000637-200104000-00009.