University of South Florida, College of Behavioral & Community Sciences, Department of Communication Sciences & Disorders, Tampa, FL 33620, USA.
Clin Neurophysiol. 2012 Jun;123(6):1131-46. doi: 10.1016/j.clinph.2011.10.003. Epub 2011 Nov 4.
Our aim was to investigate how semantic and phonological information is processed in adults who stutter (AWS) preparing to name pictures, following-up a report that event-related potentials (ERPs) in AWS evidenced atypical semantic picture-word priming (Maxfield et al., 2010).
Fourteen AWS and 14 typically-fluent adults (TFA) participated. Pictures, named at a delay, were followed by probe words. Design elements not used in Maxfield et al. (2010) let us evaluate both phonological and semantic picture-word priming.
TFA evidenced typical priming effects in probe-elicited ERPs. AWS evidenced diminished semantic priming, and reverse phonological N400 priming.
Results point to atypical processing of semantic and phonological information in AWS. Discussion considers whether AWS ERP effects reflect unstable activation of target label semantic and phonological representations, strategic inhibition of target label phonological neighbors, and/or phonological label-probe competition.
Results raise questions about how mechanisms that regulate activation spreading operate in AWS.
我们旨在调查口吃成年人(AWS)在准备命名图片时如何处理语义和语音信息,这是对先前报告的一项跟进,该报告指出事件相关电位(ERP)在 AWS 中表现出异常的语义图片-单词启动(Maxfield 等人,2010 年)。
14 名 AWS 和 14 名典型流利成年人(TFA)参与了研究。在延迟后命名图片,随后出现探针词。与 Maxfield 等人(2010 年)未使用的设计元素一起,我们可以评估语音和语义图片-单词启动。
TFA 在探针诱发的 ERP 中表现出典型的启动效应。AWS 表现出语义启动减弱,以及反向语音 N400 启动。
结果表明 AWS 中语义和语音信息的处理异常。讨论考虑了 AWS ERP 效应是否反映了目标标签语义和语音表示的不稳定激活、目标标签语音邻居的策略抑制,以及/或语音标签-探针竞争。
结果提出了关于调节激活扩散的机制在 AWS 中如何运作的问题。