Medical Clinic I Gastroenterology, Infectious Diseases, Rheumatology, Charité - Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany.
Int J Colorectal Dis. 2012 Apr;27(4):521-5. doi: 10.1007/s00384-011-1347-9. Epub 2011 Nov 9.
Capsule endoscopy (CE) is a very useful tool for the evaluation of the small intestine, but it is time consuming. The aim of this study was to compare evaluation times and detection rates in two different reading modes (single view at a speed of 10 frames per second (fps) and four images simultaneously, i.e., quadview mode at a speed of 20 fps) to find the optimum setting mode for evaluation of CE videos.
CE videos of 70 patients performed for different indications (obscure bleeding, n = 50; suspected Crohn's disease, n = 10; and suspected or complicated celiac disease, n = 10) were reviewed by investigators A and B in the two different reading modes.
The mean evaluation time using single view at 10 fps was 22 min (SD ± 9.1 min) and 11.9 min (SD ± 4.8 min) using quadview mode at 20 fps. The detection rates of angiodysplasias, erosions, small ulcers, and small polyps were only discreetly lower using the quadview mode at 20 fps. In Crohn's disease and celiac disease, the essential aspects of inflamed or atrophic mucosa segments were equally detected in both reading modes. In one case of complicated celiac disease with severe erosive jejunitis, a lymphoma-suspect lesion was overlooked in the quadview mode at 20 fps.
It is often possible to read CE videos in quadview mode at a higher speed with even so a high diagnostic yield in a shortened evaluation time.
胶囊内镜（CE）是评估小肠的非常有用的工具，但耗时较长。本研究的目的是比较两种不同阅读模式（每秒 10 帧的单视图速度（fps）和同时显示四幅图像，即每秒 20 fps 的四视图模式）的评估时间和检测率，以找到评估 CE 视频的最佳设置模式。
对 70 例因不同适应证（不明原因出血，n=50；疑似克罗恩病，n=10；疑似或复杂乳糜泻，n=10）而行 CE 的患者的 CE 视频由研究者 A 和 B 在两种不同的阅读模式下进行回顾性分析。
使用 10 fps 的单视图平均评估时间为 22 分钟（SD±9.1 分钟），使用 20 fps 的四视图模式平均评估时间为 11.9 分钟（SD±4.8 分钟）。使用 20 fps 的四视图模式时，对血管发育不良、糜烂、小溃疡和小息肉的检测率仅略有降低。在克罗恩病和乳糜泻中，两种阅读模式均能同样检测到发炎或萎缩的黏膜段的基本特征。在一例伴有严重糜烂性空肠炎的复杂乳糜泻中，20 fps 的四视图模式漏诊了疑似淋巴瘤病变。
通常可以在四视图模式下以更高的速度读取 CE 视频，同时在缩短的评估时间内保持较高的诊断率。
