Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
J Occup Environ Med. 2011 Dec;53(12):1447-51. doi: 10.1097/JOM.0b013e318237a1d0.
Epidemiologic evidence for the association between electromagnetic fields and amyotrophic lateral sclerosis, the most common form of motor neuron disease (MND), has been inconclusive. We evaluated the association between electromagnetic fields and MND among workers in occupations potentially exposed to magnetic fields
MND mortality (ICD-9 335.2) was examined in the National Longitudinal Mortality Study using multivariable proportional hazards models. Occupational exposure to magnetic fields was determined on the basis of a population-based job-exposure matrix. Age at entry, education, race, sex, and income were considered for inclusion as covariates
After adjusting for age, sex, and education, there were no increased risks of MND mortality in relation to potential magnetic field exposure, with hazard ratios around the null in all magnetic field exposure quartiles
Our study does not provide evidence for an association between magnetic field exposure and MND mortality.
电磁场与最常见的运动神经元疾病（MND）——肌萎缩性侧索硬化症之间的关联的流行病学证据尚无定论。我们评估了潜在接触磁场的职业中电磁场与 MND 之间的关联。
在国家纵向死亡率研究中，使用多变量比例风险模型检查肌萎缩性侧索硬化症死亡率（ICD-9 335.2）。根据基于人群的工作暴露矩阵确定职业接触磁场。考虑将年龄、教育程度、种族、性别和收入纳入协变量。
在校正年龄、性别和教育程度后，潜在磁场暴露与 MND 死亡率之间没有增加的风险，在所有磁场暴露四分位范围内，风险比接近零。
我们的研究没有提供磁场暴露与 MND 死亡率之间关联的证据。
