肝素包被的胶体介孔二氧化硅纳米粒子作为一种抗凝血药物递送系统，能有效地与抗凝血酶结合。 - Suppr

Heparin-coated colloidal mesoporous silica nanoparticles efficiently bind to antithrombin as an anticoagulant drug-delivery system.

作者信息

Argyo Christian, Cauda Valentina, Engelke Hanna, Rädler Joachim, Bein Gregor, Bein Thomas

机构信息

Department of Chemistry and Center for NanoScience (CeNS), University of Munich (LMU), Butenandtstrasse 5-13, Gerhardt-Ertl-Building, 81377 München, Germany.

出版信息

Chemistry. 2012 Jan 9;18(2):428-32. doi: 10.1002/chem.201102926. Epub 2011 Dec 12.

DOI:10.1002/chem.201102926

PMID:22161774

Abstract

摘要

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Heparin-coated colloidal mesoporous silica nanoparticles efficiently bind to antithrombin as an anticoagulant drug-delivery system.

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引用本文的文献

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Heparin-coated colloidal mesoporous silica nanoparticles efficiently bind to antithrombin as an anticoagulant drug-delivery system.

作者信息

Argyo Christian, Cauda Valentina, Engelke Hanna, Rädler Joachim, Bein Gregor, Bein Thomas

机构信息

Department of Chemistry and Center for NanoScience (CeNS), University of Munich (LMU), Butenandtstrasse 5-13, Gerhardt-Ertl-Building, 81377 München, Germany.

出版信息

Chemistry. 2012 Jan 9;18(2):428-32. doi: 10.1002/chem.201102926. Epub 2011 Dec 12.

DOI:10.1002/chem.201102926

PMID:22161774

Abstract

摘要

相似文献

Heparin-coated colloidal mesoporous silica nanoparticles efficiently bind to antithrombin as an anticoagulant drug-delivery system.

Chemistry. 2012 Jan 9;18(2):428-32. doi: 10.1002/chem.201102926. Epub 2011 Dec 12.

Controlled delivery using oligonucleotide-capped mesoporous silica nanoparticles.

Angew Chem Int Ed Engl. 2010 Sep 24;49(40):7281-3. doi: 10.1002/anie.201001847.

Light- and pH-responsive release of doxorubicin from a mesoporous silica-based nanocarrier.

Chemistry. 2011 Mar 14;17(12):3338-42. doi: 10.1002/chem.201002960. Epub 2011 Feb 17.

Mesoporous silica nanoparticles improve magnetic labeling efficiency in human stem cells.

Small. 2008 May;4(5):619-26. doi: 10.1002/smll.200700493.

Mesoporous silica nanoparticles for intracellular controlled drug delivery.

Small. 2010 Sep 20;6(18):1952-67. doi: 10.1002/smll.200901789.

Polyvalent nucleic acid/mesoporous silica nanoparticle conjugates: dual stimuli-responsive vehicles for intracellular drug delivery.

Angew Chem Int Ed Engl. 2011 Jan 24;50(4):882-6. doi: 10.1002/anie.201005471. Epub 2010 Dec 14.

Targeted cargo delivery in senescent cells using capped mesoporous silica nanoparticles.

Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10556-60. doi: 10.1002/anie.201204663. Epub 2012 Sep 20.

The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis.

Biomaterials. 2011 Dec;32(35):9434-43. doi: 10.1016/j.biomaterials.2011.08.042. Epub 2011 Sep 1.

Stability of small mesoporous silica nanoparticles in biological media.

Chem Commun (Camb). 2011 Jan 7;47(1):532-4. doi: 10.1039/c0cc02923h. Epub 2010 Nov 16.

Synthesis of colloidal silica nanoparticles of a tunable mesopore size and their application to the adsorption of biomolecules.

J Colloid Interface Sci. 2010 Sep 1;349(1):173-80. doi: 10.1016/j.jcis.2010.05.041. Epub 2010 May 19.

引用本文的文献

Shall We Tune? From Core-Shell to Cloud Type Nanostructures in Heparin/Silica Hybrids.

Polymers (Basel). 2022 Aug 30;14(17):3568. doi: 10.3390/polym14173568.

Current advances in nanomaterials affecting morphology, structure, and function of erythrocytes.

RSC Adv. 2021 Feb 10;11(12):6958-6971. doi: 10.1039/d0ra10124a. eCollection 2021 Feb 4.

Modulation of metal-azolate frameworks for the tunable release of encapsulated glycosaminoglycans.

Chem Sci. 2020 Jul 14;11(39):10835-10843. doi: 10.1039/d0sc01204a.

Nanoparticles for hematologic diseases detection and treatment.

Hematol Med Oncol. 2019 Jun 28;4:1000183. doi: 10.15761/hmo.1000183.

Mesoporous Silica Nanoparticles as Carriers for Therapeutic Biomolecules.

Pharmaceutics. 2020 May 7;12(5):432. doi: 10.3390/pharmaceutics12050432.

Nanoencapsulation Enhances Anticoagulant Activity of Adenosine and Dipeptide IleTrp.

Nanomaterials (Basel). 2019 Aug 23;9(9):1191. doi: 10.3390/nano9091191.

Multifunctional PLGA-based nanoparticles as a controlled release drug delivery system for antioxidant and anticoagulant therapy.

Int J Nanomedicine. 2019 Feb 26;14:1533-1549. doi: 10.2147/IJN.S174962. eCollection 2019.

Innovative Technologies Changing Cancer Treatment.

Cancers (Basel). 2018 Jun 19;10(6):208. doi: 10.3390/cancers10060208.

Thrombin-Responsive Transcutaneous Patch for Auto-Anticoagulant Regulation.

Adv Mater. 2017 Jan;29(4). doi: 10.1002/adma.201604043. Epub 2016 Nov 25.

Nanoporous silica nanoparticles as biomaterials: evaluation of different strategies for the functionalization with polysialic acid by step-by-step cytocompatibility testing.

J Mater Sci Mater Med. 2015 Mar;26(3):125. doi: 10.1007/s10856-015-5409-3. Epub 2015 Feb 18.

Heparin-coated colloidal mesoporous silica nanoparticles efficiently bind to antithrombin as an anticoagulant drug-delivery system.

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Heparin-coated colloidal mesoporous silica nanoparticles efficiently bind to antithrombin as an anticoagulant drug-delivery system.

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