Department of Nutrition, Université de Montréal, Montreal, QC, Canada.
Eur J Nutr. 2013 Feb;52(1):145-51. doi: 10.1007/s00394-011-0296-y. Epub 2012 Jan 1.
The purpose of the present secondary analysis study was to investigate the ability of the body adiposity index (BAI) to detect changes in % body fat levels before and after a weight loss intervention when compared to % body fat levels measured using dual-energy X-ray absorptiometry (DXA) and to examine the relationship between the BAI with cardiometabolic risk factors.
The study population for this secondary analysis included 132 non-diabetic obese sedentary postmenopausal women (age: 57.2 ± 4.7 years, BMI: 35.0 ± 3.7 kg/m(2)) participating in a weight loss intervention that consisted of a calorie-restricted diet with or without resistance training. We measured: (1) visceral fat using CT-scan, (2) body composition using DXA, (3) hip circumference and height from which the BAI was calculated, and (4) cardiometabolic risk factors such as insulin sensitivity (using the hyperinsulinemic-euglycemic clamp), blood pressure as well as fasting plasma lipids, hsC-reactive protein (CRP), leptin, and glucose.
Percent body fat levels for both methods significantly decreased after the weight loss intervention. In addition, the percent change in % body fat levels after the weight loss intervention was significantly different between % body fat measured using the DXA and the BAI (-4.5 ± 6.6 vs. -5.8 ± 5.9%; p = 0.03, respectively). However, we observed a good overall agreement between the two methods, as shown by the Bland-Altman analysis, for percent change in % body fat. Furthermore, similar correlations were observed between both measures of % body fat with cardiometabolic risk factors. However, results from the multiple linear regression analysis showed that % body fat using the BAI appeared to predict cardiometabolic risk factors differently than % body fat using the DXA in our cohort.
Estimating % body fat using the BAI seems to accurately trace variations of % body fat after weight loss. However, this index showed differences in predicting cardiometabolic risk factors when compared to % body fat measured using DXA.
本二次分析研究的目的是在减肥干预前后，与双能 X 射线吸收法（DXA）测量的体脂肪百分比相比，研究身体脂肪指数（BAI）检测体脂肪水平变化的能力，并检查 BAI 与心血管代谢风险因素之间的关系。
本二次分析的研究人群包括 132 名非糖尿病肥胖久坐绝经后妇女（年龄：57.2 ± 4.7 岁，BMI：35.0 ± 3.7 kg/m2），她们参加了一项减肥干预，包括限制热量的饮食加或不加抗阻训练。我们测量了：（1）CT 扫描的内脏脂肪，（2）DXA 的身体成分，（3）计算 BAI 的臀围和身高，以及（4）心血管代谢风险因素，如胰岛素敏感性（使用高胰岛素正葡萄糖钳夹法）、血压以及空腹血脂、hsC-反应蛋白（CRP）、瘦素和血糖。
两种方法的体脂肪百分比在减肥干预后均显著下降。此外，减肥干预后体脂肪百分比的变化在使用 DXA 和 BAI 测量的体脂肪百分比之间有显著差异（-4.5 ± 6.6% vs. -5.8 ± 5.9%；分别为 p = 0.03）。然而，我们观察到两种方法之间的变化百分比有很好的整体一致性，如 Bland-Altman 分析所示。此外，与心血管代谢风险因素的相关性在两种体脂肪测量方法之间也相似。然而，多元线性回归分析的结果表明，在我们的队列中，使用 BAI 估计的体脂肪百分比似乎比使用 DXA 测量的体脂肪百分比更能预测心血管代谢风险因素。
使用 BAI 估计体脂肪百分比似乎能准确地跟踪减肥后的体脂肪变化。然而，与使用 DXA 测量的体脂肪百分比相比，该指数在预测心血管代谢风险因素方面存在差异。
