城市社区婴幼儿期巨细胞病毒感染的血清流行病学
Seroepidemiology of cytomegalovirus infections during the first years of life in urban communities.
作者信息
Cabau N, Labadie M D, Vesin C, Feingold J, Boué A
出版信息
Arch Dis Child. 1979 Apr;54(4):286-90. doi: 10.1136/adc.54.4.286.
Abstract
Using indirect haemagglutination assay, combined with a collection of blood samples on blotting cards, seroepidemiological surveys of cytomegalovirus infections during early infancy have been done in different populations (French and immigrant) in urban areas. The comparison of CMV antibody status of mothers and their children at 10 months and at 2 years of age enables possible factors of viral transmission to be defined. During the first year of life, seropositive mothers were the only source of infection and they remained the main source during the second year. Socioeconomic class and educational level are determinant factors in the incidence of viral transmission.
摘要
采用间接血凝试验，并结合在吸墨卡上采集血样，在城市地区的不同人群（法国人和移民）中对婴儿早期巨细胞病毒感染进行了血清流行病学调查。比较母亲及其10个月大以及2岁孩子的巨细胞病毒抗体状态，有助于确定病毒传播的可能因素。在生命的第一年，血清反应阳性的母亲是唯一的感染源，并且在第二年她们仍然是主要感染源。社会经济阶层和教育水平是病毒传播发生率的决定性因素。
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