Chen Yung-Husan, Hwang Tsong-Long, Su Yin-Di, Chang Yu-Chia, Chen Yu-Hsin, Hong Pei-Han, Hu Li-Chung, Yen Wei-Hsuan, Hsu Hsin-Yin, Huang Shu-Jung, Kuo Yueh-Hsiung, Sung Ping-Jyun
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan.
Chem Pharm Bull (Tokyo). 2012;60(1):160-3. doi: 10.1248/cpb.60.160.
Two new 6-hydroxyeunicellin diterpenoids, cladieunicellin G (1) and 6-epi-cladieunicellin F (2), were isolated from an Indonesian octocoral Cladiella sp. The structures of eunicellins 1 and 2 were established by spectroscopic methods and 2 was found to be an epimer of the known eunicellin cladieunicellin F (3). Eunicellin 2 displayed inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.
从印度尼西亚的一种八放珊瑚Cladiella sp.中分离出了两种新的6-羟基unicellin二萜类化合物，即cladieunicellin G（1）和6-表-cladieunicellin F（2）。通过光谱方法确定了unicellins 1和2的结构，并且发现2是已知的unicellin cladieunicellin F（3）的差向异构体。Unicellin 2对人中性粒细胞中超氧阴离子的产生和弹性蛋白酶的释放具有抑制作用。
