Kumar A, Lingadurai S, Jain A, Barman N R
Department of Pharmacology, Himalayan Pharmacy Institute, Majhitar, Rangpo, East Sikkim, India .
Pharmacogn Rev. 2010 Jul;4(8):147-52. doi: 10.4103/0973-7847.70908.
This review gives an account of the current knowledge on the morphology, phytochemistry, and pharmacological aspects of Erythrina variegata. E. variegata also called Erythrina indica is a thorny deciduous tree growing to 60 feet tall. A wide range of chemical compounds have been isolated, mainly alkaloids, flavonoids, triterpenoids, and lectin. Different parts of the plant have been used in traditional medicine as nervine sedative, collyrium in opthalmia, antiasthmatic, antiepileptic, antiseptic, and as an astringent. The alkaloids extracted from the leaves of E. variegata are reported to have anti-inflammatory and analgesic activity. Isoflavonoids isolated from E. variegata having antibacterial and anthelmintic activity. E. variegata shows several other characteristic pharmacological effects like neuromuscular blocking, smooth muscle relaxant, CNS depressant, and hydrocholeretic, which are consistent with the reported uses of the plant extracts in the indigenous system of medicine. Hence the present article includes the detailed exploration of morphology, phytochemistry, and pharmacological aspects of E. variegata in an attempt to provide a direction for further research.
本文综述了刺桐的形态学、植物化学和药理学方面的现有知识。刺桐又称刺桐属印度种,是一种多刺落叶乔木,可长到60英尺高。已分离出多种化合物,主要是生物碱、黄酮类化合物、三萜类化合物和凝集素。该植物的不同部位在传统医学中用作神经镇静剂、眼科洗眼剂、抗哮喘药、抗癫痫药、防腐剂和收敛剂。据报道,从刺桐叶中提取的生物碱具有抗炎和镇痛活性。从刺桐中分离出的异黄酮具有抗菌和驱虫活性。刺桐还表现出其他几种特征性药理作用,如神经肌肉阻滞、平滑肌松弛、中枢神经系统抑制和利胆作用,这与该植物提取物在传统医学中的应用报道一致。因此,本文详细探讨了刺桐的形态学、植物化学和药理学方面,以期为进一步研究提供方向。