LaPerriere A R, Antoni M H, Schneiderman N, Ironson G, Klimas N, Caralis P, Fletcher M A
Center for the Biopsychosocial Studies of AIDS, University of Miami, Florida.
Biofeedback Self Regul. 1990 Sep;15(3):229-42. doi: 10.1007/BF01011107.
The impact of aerobic exercise training as a buffer of the affective distress and immune decrements which accompany the notification of HIV-1 antibody status in an AIDS risk group was studied. Fifty asymptomatic gay males with a pretraining fitness level of average or below (determined by predicted VO2 max) were randomly assigned to either an aerobic exercise training program or a no-contact control condition. After five weeks of training, at a point 72 hours before serostatus notification, psychometric, fitness and immunologic data were collected on all subjects. Psychometric and immunologic measures were again collected one-week postnotification. Seropositive controls showed significant increases in anxiety and depression, as well as decrements in natural killer cell number following notification whereas, seropositive exercisers showed no similar changes and in fact, resembled both seronegative groups. These findings suggest that concurrent changes in some affective and immunologic measures in response to an acute stressor might be attenuated by an experimentally manipulated aerobic exercise training intervention.
研究了有氧运动训练作为一种缓冲因素，对艾滋病风险群体中伴随HIV-1抗体状态告知而来的情感困扰和免疫功能下降的影响。五十名无症状的男同性恋者，其训练前的体能水平为平均水平或以下（通过预测的最大摄氧量确定），被随机分配到有氧运动训练计划组或非接触对照组。在训练五周后，即在血清状态告知前72小时，收集了所有受试者的心理测量、体能和免疫学数据。在告知后一周再次收集心理测量和免疫学指标。血清阳性对照组在告知后焦虑和抑郁显著增加，自然杀伤细胞数量减少，而血清阳性运动组没有类似变化，事实上，与两个血清阴性组相似。这些发现表明，通过实验操纵的有氧运动训练干预，可能会减轻对急性应激源的一些情感和免疫指标的同时变化。
