Department of Microbiology and Medical Zoology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico.
Antimicrob Agents Chemother. 2012 Apr;56(4):2119-21. doi: 10.1128/AAC.05758-11. Epub 2012 Jan 30.
During a β-lactam resistance surveillance study, 12 IMP-18-positive Pseudomonas aeruginosa isolates belonging to 9 different pulsed-field gel electrophoresis groups were identified. In nine isolates, a class I integron with a novel gene array was identified that contained bla(IMP-18) and bla(OXA-224), while in two isolates the class I integron contained bla(IMP-18) and bla(OXA-2) but in a new arrangement. Our findings show the dissemination of two novel class I integrons in P. aeruginosa from different regions of Puerto Rico.
在一项β-内酰胺类耐药性监测研究中,鉴定出 12 株属于 9 个不同脉冲场凝胶电泳群的 IMP-18 阳性铜绿假单胞菌。在 9 株菌中,鉴定出一个具有新型基因阵列的 I 类整合子,其中包含 bla(IMP-18)和 bla(OXA-224),而在另外 2 株菌中,I 类整合子包含 bla(IMP-18)和 bla(OXA-2),但排列方式不同。我们的研究结果表明,两种新型 I 类整合子在来自波多黎各不同地区的铜绿假单胞菌中传播。