Mao Xiao-Qin, Jia Xiong-Fei, Zhou Guang, Li Lu, Niu Hua, Li Feng-Liang, Liu Hai-Yun, Zheng Rui, Xu Ning
Department of Clinical Laboratory, The First People's Hospital of Yunnan Province, Kunming, China.
Asian Pac J Cancer Prev. 2011;12(9):2179-82.
The purpose of this study was to investigate relationships between green tea consumption and gastric cancer development.
A population-based case-control study including 200 cases and 200 controls was conducted in the southwest area of China from May 2010 to February 2011. A self-designed questionnaire was used to collect data on factors influencing gastric cancer development, including tea drinking, conditional logistic regression being used to calculate odds ratios (ORs) and corresponding 95% confidence intervals (95% CIs).
Cases with higher economic status had a reduced risk of gastric cancer, while those with cancer family history, drinking and smoking showed increased risk. Hot and very hot tea temperature was significantly related to high risk of gastric cancer with ORs (95%Cl) of 1.82 (1.03-3.52) and 3.07 (1.78-7.36), respectively. Further analysis indicated elevated risk of gastric cancer in former drinkers, former smokers and current drinkers when the measured tea temperature was hot.
Drinking tea at high temperature increases the gastric cancer risk, especially in drinkers and smokers.
本研究旨在调查绿茶消费与胃癌发生之间的关系。
2010年5月至2011年2月在中国西南地区开展了一项基于人群的病例对照研究，包括200例病例和200例对照。使用自行设计的问卷收集影响胃癌发生的因素数据，包括饮茶情况，采用条件逻辑回归计算比值比（OR）和相应的95%置信区间（95%CI）。
经济状况较高的病例患胃癌的风险降低，而有癌症家族史、饮酒和吸烟的病例风险增加。热茶和非常热茶的温度与胃癌高风险显著相关，OR（95%CI）分别为1.82（1.03 - 3.52）和3.07（1.78 - 7.36）。进一步分析表明，当测量的茶温度为热时，既往饮茶者、既往吸烟者和当前饮茶者患胃癌的风险升高。
高温饮茶会增加患胃癌的风险，尤其是在饮茶者和吸烟者中。
