Department of Radiology, Washington University, St. Louis, Missouri 63110, United States.
J Am Chem Soc. 2012 Mar 14;134(10):4545-8. doi: 10.1021/ja300276s. Epub 2012 Feb 28.
Modulation of the fluorescence lifetime (FLT) of CdTeSe/ZnS quantum dots (QDs) by near-IR (NIR) organic chromophores represents a new strategy for generating reproducible pH-sensing nanomaterials. The hybrid construct transfers the pH sensitivity of photolabile NIR cyanine dyes to highly emissive and long-lifetime pH-insensitive QDs, thereby inducing a reproducible FLT change from 29 ns at pH >7 to 12 ns at pH <5. This approach provides an unparalleled large dynamic FLT range for pH sensing at NIR wavelengths.
通过近红外（NIR）有机生色团来调制 CdTeSe/ZnS 量子点（QDs）的荧光寿命（FLT），为制备重现性 pH 感测纳米材料提供了一种新策略。该杂化结构将光不稳定的近红外菁染料的 pH 敏感性转移到高发射和长寿命的 pH 不敏感 QDs 上，从而在 pH > 7 时诱导出重现性的 FLT 从 29 ns 变化到 pH < 5 时的 12 ns。这种方法为在近红外波长下进行 pH 感测提供了无与伦比的大动态 FLT 范围。
