Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, United States.
Behav Res Ther. 2012 Apr;50(4):266-74. doi: 10.1016/j.brat.2012.02.006. Epub 2012 Feb 21.
Previous studies have documented that weight suppression (a person's highest adult weight minus current weight) predicts weight gain and disordered eating symptoms during treatment of bulimia spectrum disorders, but no research has examined weight suppression in individuals with anorexia nervosa (AN). Thus, this study sought to characterize weight suppression in a large sample of patients with AN (N = 185), and to evaluate whether weight suppression at admission for intensive behavioral treatment predicts weight gain and clinical outcomes at discharge. Weight suppression varied from 0 kg to 78 kg (M [SD] = 17.1 [10.8] kg) in AN patients. Higher levels of weight suppression predicted greater total weight gain, a faster rate of weight gain, and bulimic symptoms during intensive treatment even after controlling for body mass index on admission, length and type of intensive treatment received, restricting versus binge-eating/purging AN subtype, and other predictors of study outcomes. These findings converge with previous research documenting the clinical significance of weight suppression in the treatment of eating disorders. Future work is needed to replicate the current findings, and examine whether weight suppression predicts the course of AN following discharge from intensive treatment.
先前的研究记录表明，体重抑制（一个人成年后的最高体重减去当前体重）可以预测在治疗暴食症谱系障碍期间的体重增加和饮食失调症状，但没有研究检查厌食症患者的体重抑制情况。因此，本研究旨在描述大量厌食症患者（N=185）的体重抑制情况，并评估入院时的体重抑制是否预测强化行为治疗出院时的体重增加和临床结果。厌食症患者的体重抑制范围从 0 公斤到 78 公斤（M[SD]=17.1[10.8]公斤）。即使在入院时的体重指数、接受的强化治疗的时长和类型、限制型与暴食/清肠型厌食症亚型以及研究结果的其他预测因素进行控制后，更高水平的体重抑制仍预测着在强化治疗期间会出现更大的总体重增加、更快的体重增加速度和暴食症状。这些发现与先前记录体重抑制在治疗饮食失调症中的临床意义的研究结果一致。未来需要开展更多工作来复制当前的发现，并检查体重抑制是否可以预测强化治疗出院后厌食症的病程。
