孕妇与非甾体抗炎药：埃塞俄比亚孕期知识、认知及药物消费模式
Pregnant women and non-steroidal anti-inflammatory drugs: knowledge, perception and drug consumption pattern during pregnancy in ethiopia.
作者信息
Kassaw Chalelgn, Wabe Nasir Tajure
机构信息
Bole Sub-City Health Bureau, Addis Ababa, Ethiopia.
出版信息
N Am J Med Sci. 2012 Feb;4(2):72-6. doi: 10.4103/1947-2714.93377.
BACKGROUND
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the widely used drugs and are often used by pregnant women. However, they can have significant teratogenic effects. The aim of the study was to investigate pregnant women's knowledge about NSAIDs use during pregnancy and their perception and consumption pattern.
MATERIALS AND METHODS
The study was a cross sectional study on women waiting for a consultation in the selected maternity hospitals in Addis Ababa, Ethiopia. The pregnant women were selected randomly and then interviewed by using standardized questionnaires.
RESULT
A total of 224 pregnant women were involved in the study. Out of those, 203 (90.6%) of them have taken NSAIDs since the beginning of their pregnancy. About 201 (89.7%), 198 (88.4%) and 189 (84.4%) of the pregnant women considered that ibuprofen, diclofenac and aspirin are not NSAIDs respectively. Regarding analgesic effect of NSAIDs, 97 (43.3%) of the pregnant women believed that NSAIDs are effective for treating pain. Acetaminophen was considered as the most effective treatment for pain by 84 (37.50%) of the patients.
CONCLUSION
Acetaminophen is the most common analgesic that was taken by most pregnant women. The knowledge of pregnant women about NSAIDs is poor.
背景
非甾体抗炎药（NSAIDs）是广泛使用的药物之一，孕妇也经常使用。然而，它们可能具有显著的致畸作用。本研究的目的是调查孕妇对孕期使用NSAIDs的了解情况以及她们的认知和消费模式。
材料与方法
本研究是一项对埃塞俄比亚亚的斯亚贝巴选定妇产医院等待咨询的女性进行的横断面研究。随机选择孕妇，然后使用标准化问卷进行访谈。
结果
共有224名孕妇参与了该研究。其中，203名（90.6%）自怀孕开始就服用过NSAIDs。分别有201名（89.7%）、198名（88.4%）和189名（84.4%）孕妇认为布洛芬、双氯芬酸和阿司匹林不是NSAIDs。关于NSAIDs的镇痛效果，97名（43.3%）孕妇认为NSAIDs对治疗疼痛有效。84名（37.50%）患者认为对乙酰氨基酚是治疗疼痛最有效的药物。
结论
对乙酰氨基酚是大多数孕妇服用的最常见镇痛药。孕妇对NSAIDs的了解较差。
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