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多酚类物质就是药物:是时候给我们的患者开红酒处方了吗?

Polyphenols are medicine: Is it time to prescribe red wine for our patients?

作者信息

Cordova Alfredo C, Sumpio Bauer E

机构信息

Division of Surgery, Lahey Clinic Medical Center, Burlington, Massachusetts;

出版信息

Int J Angiol. 2009 Fall;18(3):111-7. doi: 10.1055/s-0031-1278336.

Abstract

Alcohol, specifically red wine, has been suggested to play a key role in the prevention of cardiovascular disease and other chronic pathologies, including cancer. Its regular and moderate consumption has been found in numerous epidemiological studies to correlate inversely with vascular disease and mortality, despite the presence of risk factors such as high consumption of saturated fats, elevated smoking and low physical activity. This phenomenon, known as the 'French Paradox', would be explained mainly by the high levels of polyphenols present in red wine, making it more advantageous than beer, spirits and even white wine. The habit of having one or two drinks of red wine every day with meals may translate to a longer, healthier and better quality of life.

摘要

酒精,尤其是红酒,被认为在预防心血管疾病和其他慢性疾病(包括癌症)方面起着关键作用。尽管存在饱和脂肪摄入量高、吸烟量大和体育活动量低等风险因素,但大量流行病学研究发现,定期适量饮用酒精与血管疾病和死亡率呈负相关。这种现象被称为“法国悖论”,主要原因可能是红酒中含有大量多酚,这使得红酒比啤酒、烈酒甚至白葡萄酒更具优势。每天用餐时喝一两杯红酒的习惯可能会带来更长、更健康和更高质量的生活。

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