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来源于海绵共生真菌层出镰刀菌 JJY40 的具有 NF-κB 抑制和抗甲型流感病毒（H1N1）活性的吡喃多烯 C-葡萄糖苷。

Pyronepolyene C-glucosides with NF-κB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp. JJY40.

机构信息

Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

出版信息

Bioorg Med Chem Lett. 2012 May 1;22(9):3188-90. doi: 10.1016/j.bmcl.2012.03.044. Epub 2012 Mar 23.

DOI:10.1016/j.bmcl.2012.03.044
PMID:22487178
Abstract

A new pyronepolyene C-glucoside, named iso-D8646-2-6 (1) together with the known related compound D8646-2-6 (2), was isolated from the sponge-associated fungus Epicoccum sp. JJY40. They showed NF-κB inhibitory and anti-influenza A viral (H1N1) activities.

摘要

一种新的吡喃多烯 C-糖苷，命名为 iso-D8646-2-6（1），与已知的相关化合物 D8646-2-6（2）一起，从海绵相关真菌层出镰刀菌 JJY40 中分离得到。它们具有 NF-κB 抑制和抗甲型流感病毒（H1N1）活性。

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