Institute of Marine Biology and Natural Products, Department of Ocean Science and Engineering, Zhejiang University, Hangzhou 310058, People's Republic of China.
Carbohydr Res. 2012 Jul 1;355:45-9. doi: 10.1016/j.carres.2012.04.009. Epub 2012 Apr 20.
Three novel lignan glycosides, 1-[4-(β-glucopyranosyl (1→2)-[β-glucopyranosyl (1→6)]-β-glucopyranosyloxy)-3-methoxyphenyl]-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-1,3-propanediol (1), 2,3-dihydro-2-[4-(β-glucopyranosyl (1→2)-[β-glucopyranosyl (1→6)]-β-glucopyranosyloxy)-3-methoxyphenyl]-3-(hydroxymethyl)-7-methoxy-5-benzofuranpropanol (2), 7-hydroxy-9'-β-glucopyranosyloxyl secoisolariciresinol (3) and two known lignans were isolated from exocarp of Castanea henryi. Their structures were established by spectroscopic means, and their tyrosinase inhibitory potentials were evaluated in vitro using mushroom tyrosinase.
三种新的木脂素糖苷，1-[4-(β-吡喃葡萄糖基(1→2)-[β-吡喃葡萄糖基(1→6)]-β-吡喃葡萄糖基氧基)-3-甲氧基苯基]-2-[4-(3-羟丙基)-2-甲氧基苯氧基]-1,3-丙二醇（1）、2,3-二氢-2-[4-(β-吡喃葡萄糖基(1→2)-[β-吡喃葡萄糖基(1→6)]-β-吡喃葡萄糖基氧基)-3-甲氧基苯基]-3-(羟甲基)-7-甲氧基-5-苯并呋喃丙烷醇（2）、7-羟基-9'-β-吡喃葡萄糖基氧基-去甲二氢愈创木脂酸（3）以及两种已知的木脂素，从栗的外果皮中分离得到。它们的结构通过光谱手段确定，并在体外使用蘑菇酪氨酸酶评估了它们的酪氨酸酶抑制潜力。
