Biomedical Diagnostics Institute, National Centre for Sensor Research, School of Physical Sciences, Dublin City University, Ireland.
Curr Opin Chem Biol. 2012 Aug;16(3-4):409-14. doi: 10.1016/j.cbpa.2012.06.002. Epub 2012 Jul 9.
Over the past two decades, centrifugal microfluidic systems have successfully demonstrated their capability for robust, high-performance liquid handling to enable modular, multi-purpose lab-on-a-chip platforms for a wide range of life-science applications. Beyond the handling of homogeneous liquids, the unique, rotationally controlled centrifugal actuation has proven to be specifically advantageous for performing cell and particle handling and assays. In this review we discuss technologies to implement two important steps for cell handling, namely separation and capturing/counting.
在过去的二十年中，离心微流控系统已经成功地展示了其强大的、高性能的液体处理能力，为各种生命科学应用实现了模块化、多用途的芯片实验室平台。除了处理均匀液体外，独特的、旋转控制的离心致动已被证明特别有利于进行细胞和颗粒处理和分析。在这篇综述中，我们讨论了实现细胞处理两个重要步骤的技术，即分离和捕获/计数。
