Wagner U, Schlebusch H, van der Ven H, van der Ven K, Diedrich K, Krebs D
Centre for Obstetrics and Gynaecology, University of Bonn.
J Clin Chem Clin Biochem. 1990 Oct;28(10):683-8.
In order to assess the burden of environmental pollutants in the genital tract, 12 different chlorinated hydrocarbons were determined in 152 samples of follicular, seminal and cervical fluids from sterility patients in the in vitro fertilization programme at the Centre for Obstetrics and Gynaecology of the University of Bonn. The lowest concentrations were found in the follicular fluids of patients who eventually became pregnant by in vitro fertilization. Higher concentrations were found in patients with sterility of unknown origin. Concentrations in the cervical secretion were up to twenty times higher than those in the seminal or follicular fluids. The results show that considerable concentrations of chlorinated hydrocarbons may be present in parts of the reproductive system, and that these compounds accumulate in the reception zone for spermatozoa. Certain pollutants therefore probably contribute to infertility.
为了评估生殖道中环境污染物的负担，在波恩大学妇产科中心的体外受精项目中，对152例不育患者的卵泡液、精液和宫颈液样本中的12种不同氯代烃进行了测定。在最终通过体外受精怀孕的患者的卵泡液中发现了最低浓度。在不明原因不育的患者中发现了较高浓度。宫颈分泌物中的浓度比精液或卵泡液中的浓度高出多达20倍。结果表明，生殖系统的某些部位可能存在相当浓度的氯代烃，并且这些化合物在精子的接收区域积聚。因此，某些污染物可能导致不育。
