Division of Cardiology, Lehigh Valley Health Network, Allentown, PA 18103, USA.
J Clin Hypertens (Greenwich). 2012 Aug;14(8):502-6. doi: 10.1111/j.1751-7176.2012.00647.x. Epub 2012 May 21.
Prevalence of the metabolic syndrome (MetS) is high in the United States and is associated with increased risk of cardiovascular disease and diabetes. The authors examined whether the prevalence of the MetS and its components differs across age groups. Data were analyzed from 4 National Health and Nutrition Examination Surveys between the years 1999 and 2006. Prevalence of MetS as defined by the Third Report of the Adult Treatment Panel criteria and prevalence of associated cardiac risk factors were determined in 41,474 participants aged 18 years and older without a history of cardiovascular disease (CVD). All estimates were weighted. Prevalence of MetS among asymptomatic adults without CVD was 20.5% and remained stable for the total population during survey periods. Prevalence of MetS increased with age: 6.6% in young adults (age 18-29 years) and 34.6% in older adults (70 and older). Components of MetS differed between young and old adults. Young adults had lower levels of high-density lipoprotein cholesterol, less glucose intolerance, and less hypertension. This study provides an estimate of MetS prevalence in asymptomatic adults in the United States during an 8-year period revealing that MetS affects a large number of Americans. Components of MetS differ between young and old adults and may have important implications in their clinical management.
代谢综合征(MetS)在美国的患病率很高,与心血管疾病和糖尿病的风险增加有关。作者研究了代谢综合征及其各组成部分在不同年龄组中的患病率是否存在差异。本研究分析了 1999 年至 2006 年间进行的 4 次全国健康和营养调查的数据。在无心血管疾病(CVD)病史的 41474 名 18 岁及以上成年人中,根据成人治疗专家组第三次报告的标准确定代谢综合征的患病率以及相关心脏危险因素的患病率。所有估计均经过加权处理。无症状成年人中无 CVD 的代谢综合征患病率为 20.5%,在调查期间总人群中保持稳定。代谢综合征的患病率随年龄增长而增加:年轻人(18-29 岁)为 6.6%,老年人(70 岁及以上)为 34.6%。年轻和老年成年人之间的代谢综合征组成部分存在差异。年轻人的高密度脂蛋白胆固醇水平较低,葡萄糖耐量异常和高血压的发生率较低。本研究提供了在 8 年期间美国无症状成年人中代谢综合征的患病率估计值,表明代谢综合征影响了大量美国人。年轻和老年成年人之间的代谢综合征组成部分存在差异,这可能对其临床管理具有重要意义。