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自主性、积极关系和白细胞介素-6:性别特异性影响的证据。

Autonomy, positive relationships, and IL-6: evidence for gender-specific effects.

机构信息

Department of Psychology, University of Kentucky, 005 Kastle Hall, Lexington, KY 40506-0044, USA.

出版信息

Br J Health Psychol. 2013 May;18(2):420-38. doi: 10.1111/j.2044-8287.2012.02085.x. Epub 2012 Aug 22.

DOI:10.1111/j.2044-8287.2012.02085.x
PMID:22908985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3925399/
Abstract

OBJECTIVES

A body of evidence indicates that women value relationship-centred aspects of well-being more than men do, while men value autonomy-centred aspects of well-being more than women do. The current study examined whether gender moderates relations between autonomy and positive relationships and interleukin-6 (IL-6), a cytokine associated with inflammatory processes. Aspects of well-being consistent with gender-linked values were expected to be most health protective such that positive relationships would predict lower IL-6 only or more strongly in women, and autonomy would predict lower IL-6 only or more strongly in men.

METHODS

In the first study, a sample of 119 older adults (55% female) living in Kentucky were visited in their homes for interviews and blood draws. In the second study, a sample of 1,028 adults (45% female) living across the United States underwent a telephone interview followed by a visit to a research centre for blood draws.

RESULTS

In the Kentucky sample, autonomy was quadratically related to IL-6 such that moderate autonomy predicted higher IL-6; this effect was stronger in men. In the US national sample, more positive relationships were associated with lower IL-6 in women only. When the national sample was restricted to match the Kentucky sample, moderate autonomy was again associated with higher IL-6 in men only.

CONCLUSIONS

Results provide preliminary evidence for gender-specific effects of positive relationships and autonomy on IL-6. Further work is needed to establish the generalizability of these effects to different ages, cultures, and health statuses.

STATEMENT OF CONTRIBUTION

What is already known on this subject? A host of previous work indicates that women value relationship-centred aspects of well-being more than men, while men value autonomy-centred aspects of well-being more than women. Further, there is some evidence suggesting that well-being consistent with gender-linked values is more health protective, such that relationships are more protective for women than for men, while autonomy is more protective for men than for women. What does this study add We provide preliminary support for the hypothesis that gender moderates the associations of autonomy and positive relationships with IL-6. Specifically, higher levels of positive relationships may be associated with lower IL-6 in women only, whereas moderate levels of autonomy may be associated with higher IL-6 in males only, particularly among older adults.

摘要

目的

大量证据表明,女性比男性更重视幸福感中以关系为中心的方面,而男性则比女性更重视幸福感中以自主为中心的方面。本研究旨在检验性别是否调节自主与积极关系和白细胞介素-6(IL-6)之间的关系,白细胞介素-6 是一种与炎症过程相关的细胞因子。与性别相关的价值观相一致的幸福感方面预计将具有最大的健康保护作用,即积极的关系仅在女性中或在女性中更强烈地预测较低的 IL-6,而自主仅在男性中或在男性中更强烈地预测较低的 IL-6。

方法

在第一项研究中,对肯塔基州 119 名(55%为女性)居住在其家中的老年人进行了家访访谈和血液抽取。在第二项研究中,来自美国各地的 1028 名成年人(45%为女性)接受了电话访谈,随后前往研究中心进行血液抽取。

结果

在肯塔基州的样本中,自主与 IL-6 呈二次关系,即适度的自主预测 IL-6 更高;这种效应在男性中更强。在美国全国样本中,仅在女性中,更多的积极关系与较低的 IL-6 相关。当全国样本被限制以匹配肯塔基州的样本时,适度的自主再次与男性的更高 IL-6 相关。

结论

结果为积极关系和自主对 IL-6 的性别特异性影响提供了初步证据。需要进一步的工作来确定这些影响在不同年龄、文化和健康状况下的普遍性。

贡献说明

关于这个主题,已经知道了什么?大量先前的工作表明,女性比男性更重视幸福感中以关系为中心的方面,而男性则比女性更重视幸福感中以自主为中心的方面。此外,有一些证据表明,与性别相关的价值观相一致的幸福感更具健康保护作用,例如,关系对女性的保护作用大于男性,而自主对男性的保护作用大于女性。本研究有何补充?我们初步支持假设,即性别调节自主与积极关系与 IL-6 之间的关联。具体而言,较高水平的积极关系可能仅与女性的较低 IL-6 相关,而适度的自主水平可能仅与男性的较高 IL-6 相关,尤其是在老年人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f47/3925399/82417c575186/nihms550197f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f47/3925399/e1fc5171bd67/nihms550197f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f47/3925399/0c0d302532ef/nihms550197f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f47/3925399/82417c575186/nihms550197f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f47/3925399/e1fc5171bd67/nihms550197f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f47/3925399/0c0d302532ef/nihms550197f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f47/3925399/82417c575186/nihms550197f3.jpg

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本文引用的文献

1
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J Pers Soc Psychol. 2011 Jul;101(1):164-84. doi: 10.1037/a0023663.
2
The impact of perceived social support and negative life events on bulimic symptoms.感知到的社会支持和负面生活事件对暴食症状的影响。
Eat Behav. 2011 Jan;12(1):44-8. doi: 10.1016/j.eatbeh.2010.11.002. Epub 2010 Nov 11.
3
Genetic and environmental influences on girls' and boys' gender-typed and gender-neutral values.
汉族人群中klotho基因和白细胞介素6基因多态性与衰老的关联
J Nutr Health Aging. 2014 Dec;18(10):900-4. doi: 10.1007/s12603-014-0470-z.
4
Repetitive thought dimensions, psychological well-being, and perceived growth in older adults: a multilevel, prospective study.老年人的重复思维维度、心理健康和感知成长:一项多层次前瞻性研究。
Anxiety Stress Coping. 2015;28(3):287-302. doi: 10.1080/10615806.2014.947285. Epub 2014 Aug 19.
遗传和环境对女孩和男孩的性别类型和性别中立价值观的影响。
Dev Psychol. 2011 May;47(3):726-31. doi: 10.1037/a0021910.
4
Associations of gene sequence variation and serum levels of C-reactive protein and interleukin-6 with Alzheimer's disease and dementia.基因序列变异与 C-反应蛋白和白细胞介素-6 血清水平与阿尔茨海默病和痴呆的关联。
J Alzheimers Dis. 2011;23(2):361-9. doi: 10.3233/JAD-2010-101671.
5
Socioeconomic and psychosocial predictors of interleukin-6 in the MIDUS national sample.美国中年人大样本中白细胞介素-6的社会经济和心理社会预测因素
Health Psychol. 2010 Nov;29(6):626-35. doi: 10.1037/a0021360.
6
Gender, values, and occupational interests among children, adolescents, and adults.儿童、青少年和成人的性别、价值观和职业兴趣。
Child Dev. 2010 May-Jun;81(3):778-96. doi: 10.1111/j.1467-8624.2010.01433.x.
7
Cross-national variation in the size of sex differences in values: effects of gender equality.价值观中性别差异大小的跨国变化:性别平等的影响。
J Pers Soc Psychol. 2009 Jul;97(1):171-85. doi: 10.1037/a0015546.
8
Association of socioeconomic status with inflammation markers in black and white men and women in the Coronary Artery Risk Development in Young Adults (CARDIA) study.在冠状动脉风险发展在年轻人(CARDIA)研究中,社会经济地位与黑人和白人男性和女性的炎症标志物的关联。
Soc Sci Med. 2009 Aug;69(3):451-9. doi: 10.1016/j.socscimed.2009.05.018. Epub 2009 Jun 11.
9
Peer relationships and diabetes: retrospective and ecological momentary assessment approaches.同伴关系与糖尿病:回顾性和生态瞬时评估方法
Health Psychol. 2009 May;28(3):273-82. doi: 10.1037/a0013784.
10
To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers.评估、控制、排除:生物行为因素对循环炎症标志物的影响。
Brain Behav Immun. 2009 Oct;23(7):887-97. doi: 10.1016/j.bbi.2009.04.005. Epub 2009 Apr 21.