Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200032, China.
Cancer Epidemiol. 2012 Dec;36(6):e354-8. doi: 10.1016/j.canep.2012.08.004. Epub 2012 Sep 1.
Little is known about the etiology of pancreatic cancer. Epidemiological studies on tea consumption and pancreatic cancer risk have been inconclusive. The purpose of the present study was to investigate the association between green tea drinking and the risk of pancreatic cancer in urban Shanghai, China.
In this population-based case-control study conducted in urban Shanghai, 908 cases of pancreatic cancer and 1067 healthy controls were recruited. Information on tea drinking, including type of tea, amount of tea consumption, temperature of tea, and the duration of regular tea drinking, were collected via interview questionnaire.
We examined the association of multiple tea drinking habits with the risk of pancreatic cancer. In women, regular green tea drinking was associated with 32% reduction of pancreatic cancer risk (OR 0.68, 95% CI 0.48-0.96), compared to those who did not drink tea regularly. Increased consumption and longer duration of tea drinking were both associated with reduced pancreatic cancer risk in women. Among regular tea drinkers, lower temperature of tea was associated with reduced risk of pancreatic cancer in both men and women, independent of amount or duration of tea drinking.
Habits of green tea drinking, including regular drinking, amount of consumption, persistence of the habit, and tea temperature, may lower pancreatic cancer risk.
胰腺癌的病因知之甚少。关于饮茶与胰腺癌风险的流行病学研究尚无定论。本研究旨在探讨饮茶与中国上海城市人群胰腺癌风险的关系。
本研究采用基于人群的病例对照研究，在上海市区招募了 908 例胰腺癌患者和 1067 名健康对照者。通过访谈问卷收集了有关饮茶的信息，包括饮茶类型、饮茶量、饮茶温度以及饮茶习惯的持续时间。
我们研究了多种饮茶习惯与胰腺癌风险的关系。在女性中，与不规律饮茶者相比，经常饮用绿茶可使胰腺癌风险降低 32%（OR 0.68，95%CI 0.48-0.96）。饮茶量增加和饮茶时间延长均与女性胰腺癌风险降低相关。在经常饮茶者中，无论饮茶量或持续时间如何，较低的饮茶温度与男女患胰腺癌的风险降低均相关，且独立于饮茶量或持续时间。
绿茶的饮用习惯，包括有规律地饮用、饮茶量、持续时间和饮茶温度，可能降低胰腺癌的风险。
