Aldous E W, Fuller C M, Ridgeon J H, Irvine R M, Alexander D J, Brown I H
AHVLA-Weybridge, Surrey, UK.
Transbound Emerg Dis. 2014 Apr;61(2):134-9. doi: 10.1111/tbed.12006. Epub 2012 Sep 11.
Newcastle disease (ND), caused by virulent strains of avian paramyxovirus type 1 (APMV-1), is considered throughout the world as one of the most important animal diseases. For over three decades now, there has been a continuing panzootic caused by a variant virulent APMV-1 strain, so-called pigeon paramyxovirus type 1 (PPMV-1), primarily in racing pigeons, which has also spread to wild birds and poultry. PPMV-1 isolations have been made in Great Britain every year since 1983. In this study, we have completed a comparative phylogenetic analysis based on a 374 nucleotide section of the fusion protein gene of 63 isolates of PPMV-1 that were isolated over a 26-year period; 43 of these were sequenced for this study. Phylogenetic analysis of these sequences revealed that all were closely related and placed in the genetic sublineage 4b (VIb), subdivision 4biif.
新城疫（ND）由1型禽副粘病毒（APMV-1）的强毒株引起，在全球范围内被视为最重要的动物疾病之一。三十多年来，一种变异的APMV-1强毒株，即所谓的1型鸽副粘病毒（PPMV-1），一直在持续引发大流行，主要感染赛鸽，并且已经传播到野生鸟类和家禽中。自1983年以来，英国每年都有PPMV-1分离株。在本研究中，我们基于26年间分离的63株PPMV-1融合蛋白基因的374个核苷酸片段完成了比较系统发育分析；其中43株为此研究进行了测序。对这些序列的系统发育分析表明，所有序列都密切相关，并属于遗传亚系4b（VIb），细分4biif。
