Department of Pediatric Neurology, Dr. Sami Ulus Children's Health and Diseases Training and Research Hospital, Babür Cd. Altındağ, 06090 Ankara, Turkey.
Eur J Pediatr. 2012 Dec;171(12):1815-21. doi: 10.1007/s00431-012-1826-1. Epub 2012 Sep 15.
To investigate the biological and socioeconomic factors associated with developmental attainment in socioeconomically disadvantaged children. This study was performed at the Dr. Sami Ulus Children's Health and Diseases Training and Research Hospital, between January and December 2010. The effects of biological, socioeconomic risk factors on developmental delay were investigated in 692 children (3 months-5 years) using the Denver II. Low-level maternal education (odds ratio [OR], 11.118; 95 % CI, 4.211-29.351), low-level paternal education (OR, 2.107; 95 % CI, 1.333-3.331), low-level household income (OR, 2.673; 95 % CI, 1.098-2.549), and ≥ 3 children in the family (OR, 1.871; 95 % CI, 1.206-2.903) were strongly associated with abnormal on Denver II; biological risk factors, including birth weight, gestational age at birth, and maternal age at birth <20 years, were correlated with suspect on Denver II results based on univariate analysis. Low-level maternal education (OR, 6.281; 95 % CI, 2.193-17.989), premature birth (32-36 weeks of gestation; OR, 0.535; 95 % CI, 0.290-0.989) were strongly associated with abnormal on Denver II results, and low-level paternal education (OR, 3.088; 95 % CI, 1.521-6.268), low-level household income (OR, 1.813; 95 % CI, 1.069-3.077), low birth weight (<1,500 g; OR, 3.003; 95 % CI, 1.316-6.854), premature birth (27-31 weeks of gestation; OR, 2.612; 95 % CI, 1.086-6.286), and maternal age at birth <20 years (OR, 3.518; 95 % CI, 1.173-10.547) were strongly associated with suspect on Denver II results based on multivariate analysis.
Socioeconomic risk factors were observed to be as important as biological risk factors in the development of children aged 3 months-5 years.
研究与社会经济地位低下的儿童发育相关的生物学和社会经济学因素。本研究于 2010 年 1 月至 12 月在 Dr. Sami Ulus 儿童健康与疾病培训与研究医院进行。使用 Denver II 对 692 名（3 个月至 5 岁）儿童的生物学、社会经济风险因素对发育迟缓的影响进行了调查。低水平的母亲教育（比值比[OR]，11.118；95%置信区间[CI]，4.211-29.351）、低水平的父亲教育（OR，2.107；95%CI，1.333-3.331）、低水平家庭收入（OR，2.673；95%CI，1.098-2.549）和≥3 个孩子的家庭（OR，1.871；95%CI，1.206-2.903）与 Denver II 异常明显相关；生物风险因素，包括出生体重、出生时胎龄和母亲 20 岁以下的年龄，与基于单变量分析的 Denver II 可疑结果相关。低水平的母亲教育（OR，6.281；95%CI，2.193-17.989）、早产（32-36 周）（OR，0.535；95%CI，0.290-0.989）与 Denver II 异常结果强烈相关，低水平的父亲教育（OR，3.088；95%CI，1.521-6.268）、低水平家庭收入（OR，1.813；95%CI，1.069-3.077）、低出生体重（<1500 g；OR，3.003；95%CI，1.316-6.854）、早产（27-31 周）（OR，2.612；95%CI，1.086-6.286）和母亲 20 岁以下的年龄（OR，3.518；95%CI，1.173-10.547）与基于多变量分析的 Denver II 可疑结果强烈相关。
社会经济风险因素与生物学风险因素一样，对 3 个月至 5 岁儿童的发育至关重要。
